# Coexistence of Lichen Planus and Squamous Cell Carcinoma on Sun-Exposed Skin: A Case Report

**Authors:** Adelina Velikova, Anastasia I Bekyarova, Andreya Kirilova, Kristina Naydenova, George S Stoyanov, Hristo Popov

PMC · DOI: 10.7759/cureus.86194 · Cureus · 2025-06-17

## TL;DR

This case report describes a 79-year-old man with both lichen planus and squamous cell carcinoma on sun-exposed facial skin.

## Contribution

The novelty lies in documenting the coexistence of LP and SCC in a single patient with a history of actinic keratosis.

## Key findings

- A 79-year-old male had moderately differentiated cutaneous SCC on his face.
- The SCC developed alongside preexisting actinic keratosis and lichen planus.
- The case highlights potential progression of chronic skin lesions to malignancy in sun-exposed areas.

## Abstract

Lichen planus (LP) is a chronic idiopathic skin disorder that has a predilection for sun-exposed areas. Although rare, there is a possibility that chronic LP lesions could progress to squamous cell carcinoma (SCC), a non-melanocytic malignant skin neoplasm. Cumulative exposure to ultraviolet radiation, particularly in individuals with lighter skin tones, is one of the leading risk factors for cutaneous SCC (cSCC). In this report, we present a case of a 79-year-old male patient who was diagnosed with a moderately differentiated cSCC with facial localization. This condition developed on the background of preexisting actinic keratosis, and was accompanied by a LP.

## Linked entities

- **Diseases:** Lichen Planus (MONDO:0006572), Squamous Cell Carcinoma (MONDO:0005096), actinic keratosis (MONDO:0005173)

## Full-text entities

- **Diseases:** actinic keratosis (MESH:D055623), non-melanocytic malignant skin neoplasm (MESH:D012878), SCC (MESH:D002294), skin disorder (MESH:D012871), LP (MESH:D008010)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12270506/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12270506/full.md

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Source: https://tomesphere.com/paper/PMC12270506