# Eustachian Valve Endocarditis Secondary to Candida glabrata Complicated by Frailty and Acute COVID-19 Infection

**Authors:** Brittany L Davis, Ronald T Garry

PMC · DOI: 10.7759/cureus.86198 · Cureus · 2025-06-17

## TL;DR

An 82-year-old man with multiple health issues developed a rare case of eustachian valve endocarditis caused by Candida glabrata and complicated by frailty and acute COVID-19.

## Contribution

This report adds to the limited literature on eustachian valve endocarditis in older adults with complex comorbidities.

## Key findings

- Eustachian valve endocarditis was diagnosed in an 82-year-old male with a history of aortic aneurysm and septicemia.
- The infection was caused by Candida glabrata and complicated by frailty and acute COVID-19.
- The case highlights the challenges in managing endocarditis in elderly patients with multiple comorbidities.

## Abstract

Transesophageal echocardiograms have revealed that the eustachian valve persists in a small proportion of the adult population. Only a few cases of eustachian valve endocarditis have previously been reported in older adults. This case report describes an 82-year-old male patient with eustachian valve endocarditis. He had a remote history of infrarenal abdominal aortic aneurysm post endovascular leak repair, recent septicemia from Streptococcus mitis from an infected tooth, frailty, diabetes, and immunosenescence. He was found to have developed bacteremia and fungemia.

## Linked entities

- **Diseases:** abdominal aortic aneurysm (MONDO:0005350), diabetes (MONDO:0005015), COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** bacteremia (MESH:D016470), infected tooth (MESH:D007239), fungemia (MESH:D016469), diabetes (MESH:D003920), Eustachian Valve Endocarditis (MESH:D004696), leak (MESH:D019559), COVID-19 Infection (MESH:D000086382), septicemia (MESH:D018805), abdominal aortic aneurysm (MESH:D017544)
- **Species:** Streptococcus mitis (species) [taxon 28037], Homo sapiens (human, species) [taxon 9606], Nakaseomyces glabratus (species) [taxon 5478]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12269335/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12269335/full.md

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Source: https://tomesphere.com/paper/PMC12269335