# An Unusual Case of Chronic Delimited Rhinosinusal Mucormycosis With Secondary Cutaneous Involvement in a Patient With Ataxia-Telangiectasia Syndrome

## TL;DR

A 15-year-old with ataxia-telangiectasia syndrome developed a rare chronic fungal infection affecting the sinuses and skin.

## Contribution

This case report highlights an unusual presentation of mucormycosis in a patient with ataxia-telangiectasia syndrome.

## Key findings

- The patient had a six-month history of recurrent sinusitis unresponsive to treatment.
- Secondary cutaneous involvement was observed with ulcerated nodules and crusted plaques.
- The case suggests a shift in the epidemiology of opportunistic infections towards new risk factors.

## Abstract

Mucormycosis is an immunosuppression-related fungal infection. This pathogen usually manifests as an acute and rapidly progressive, deforming, and lethal disease, but chronic forms of zygomycosis occur rarely. Here we present a case of a 15-year-old female with ataxia-telangiectasia syndrome, reporting a six-month history of recurrent sinusitis and an atypical secondary skin infection characterized by ulcerated nodules and crusted plaques, unresponsive to multiple treatments. This case highlights the changing epidemiology of opportunistic infections, which were usually confined to specific immunosuppressive diseases but are recently presenting a shift towards their associated risk factors and comorbidities.