# Pilomatrixoma of the Eyelid in an 83-Year-Old Woman: A Rare Case in the Elderly

**Authors:** Dina Yazidi, Nicolas De Saint-Aubain, Sebastien Michiels

PMC · DOI: 10.7759/cureus.86187 · Cureus · 2025-06-17

## TL;DR

An 83-year-old woman with a history of breast cancer had a rare eyelid tumor called pilomatrixoma, which was successfully removed and did not recur.

## Contribution

This paper reports a rare case of pilomatrixoma in an elderly patient with a history of breast cancer.

## Key findings

- Pilomatrixoma was confirmed via histopathological analysis and completely excised with clear margins.
- The patient had no recurrence at one-month follow-up.
- The case emphasizes considering pilomatrixoma in differential diagnoses for head and neck lesions in elderly patients.

## Abstract

Pilomatrixoma is a rare subcutaneous tumor originating from the cellular matrix of hair follicles. While it predominantly arises during the first two decades of life, its occurrence in elderly patients is exceedingly rare. We present the case of an 83-year-old woman with a recently growing, indurated nodule located on the right upper eyelid. Her medical history included left breast cancer treated with tumorectomy, radiotherapy, and chemotherapy, with remission since 2012. Given her advanced age and oncological history, differential diagnoses included malignant tumors, metastasis, or recurrence of breast cancer involving the head and neck region. Histopathological analysis confirmed the diagnosis of pilomatrixoma, which was completely excised with clear margins. The postoperative course was uneventful, and no recurrence was observed at one-month follow-up. This case highlights the importance of including pilomatrixoma in the differential diagnosis of head and neck lesions in elderly patients.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** malignant (MESH:D009369), breast cancer (MESH:D001943), Pilomatrixoma (MESH:D018296), head and neck lesions (MESH:D006258)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12268492/full.md

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Source: https://tomesphere.com/paper/PMC12268492