# Unusual Presentation of Mycobacterium abscessus Thigh Mass: A Case Report

**Authors:** Ryan J. Blake, Grant R. McChesney, H. James Williams, Steven M. Holland, Allison M. Lastinger

PMC · DOI: 10.1155/crdi/6970929 · Case Reports in Infectious Diseases · 2025-07-09

## TL;DR

A 61-year-old woman developed a rare thigh abscess caused by Mycobacterium abscessus, requiring surgery and antibiotics due to its antibiotic resistance.

## Contribution

Presents a rare case of M. abscessus intramuscular abscess without typical risk factors, emphasizing the need for early diagnosis and treatment.

## Key findings

- M. abscessus can cause intramuscular abscesses even in individuals without obvious risk factors.
- Treatment required surgical resection and a complex antibiotic regimen due to macrolide resistance.
- Early identification and combined therapy are crucial for managing such infections.

## Abstract

Mycobacterium abscessus is a rapidly growing non-tuberculous Mycobacterium (NTM) primarily associated with pulmonary infections, particularly in individuals with underlying lung conditions. While soft tissue infections are less common, their incidence has been increasing. These infections are challenging to treat due to inherent resistance to many antibiotics obtained through spontaneous mutation as well as physical characteristics of the microbes. The case presented here describes a 61-year-old female without obvious risk factors for mycobacterial infection who developed an intramuscular abscess over a 2-year period following a mechanical fall. Surgical resection with a complex antibiotic regimen was required based on macrolide resistance and a lack of established treatment plans for such a rare presentation. This case highlights the increasing incidence of NTM and the variable clinical presentation. Early identification with a combination of surgery and antibiotics is usually indicated to successfully manage these infections. Even without obvious risk factors, NTM infection should be considered in the presence of soft tissue and intramuscular abscesses.

## Full-text entities

- **Diseases:** NTM infection (MESH:D009164), intramuscular abscess (MESH:D006391), infections (MESH:D007239), pulmonary infections (MESH:D012141), abscesses (MESH:D000038), Mycobacteroides abscessus (MESH:D009165)
- **Chemicals:** macrolide (MESH:D018942)
- **Species:** Mycobacteroides abscessus (species) [taxon 36809]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12267892/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12267892/full.md

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Source: https://tomesphere.com/paper/PMC12267892