# Effect of an Eclectic Physiotherapeutic Approach on Physical Performance, Fatigue, and Hospital Anxiety and Depression in a Patient Receiving Radiotherapy for Squamous Cell Carcinoma of the Buccal Mucosa: A Case Report

**Authors:** Tushara Nair, G. Palani Kumar

PMC · DOI: 10.7759/cureus.86172 · Cureus · 2025-06-16

## TL;DR

A personalized physiotherapy program improved physical performance and reduced fatigue, anxiety, and depression in a patient undergoing radiotherapy for mouth cancer.

## Contribution

This case report demonstrates the effectiveness of a personalized eclectic physiotherapy approach in managing cancer-related symptoms during radiotherapy.

## Key findings

- The physiotherapy protocol improved the patient's physical performance as measured by the Timed Up and Go Test.
- Cancer-related fatigue, anxiety, and depression were significantly reduced following the intervention.
- An eclectic mix of exercises and recreational activities was effective in a clinical setting.

## Abstract

Squamous cell carcinoma of the buccal mucosa is one of the most common tumors among head and neck cancers. It first involves the superficial layer of the buccal mucosa and then slowly starts infiltrating into the deeper tissues as well. A 45-year-old female patient diagnosed with squamous cell carcinoma of the right buccal mucosa underwent a marginal mandibulectomy with pectoralis major myocutaneous flap reconstruction and was admitted for radiotherapy sessions. She also had a history of fatigue and decreased physical performance. A personalized physiotherapy protocol was formulated, which included general mobility exercises, strengthening exercises, light aerobics, yoga, relaxation, and recreational activities. The Timed Up and Go Test was used to assess physical performance, the Functional Assessment of Chronic Illness Therapy Fatigue Scale was used to assess cancer-related fatigue, and the Hospital Anxiety and Depression Scale was used to assess the anxiety and depression due to hospital admission. This case study concluded that this personalized eclectic approach definitely improves physical performance, decreases fatigue, anxiety, and depression.

## Linked entities

- **Diseases:** squamous cell carcinoma (MONDO:0005096), buccal mucosa cancer (MONDO:0004645), anxiety (MONDO:0005618), depression (MONDO:0002050)

## Full-text entities

- **Diseases:** cancer (MESH:D009369), Anxiety (MESH:D001007), Fatigue (MESH:D005221), Squamous Cell Carcinoma of the Buccal Mucosa (MESH:D002294), head and neck cancers (MESH:D006258), Depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12267874/full.md

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Source: https://tomesphere.com/paper/PMC12267874