# Persistent trigeminal artery linked with partial duplication of the anterior communicating artery

**Authors:** George Triantafyllou, Panagiotis Papadopoulos-Manolarakis, George Tsakotos, Anastasia Triantafyllou, Maria Piagkou

PMC · DOI: 10.1007/s00276-025-03687-9 · Surgical and Radiologic Anatomy · 2025-07-16

## TL;DR

A rare case of a persistent embryonic artery coexisting with an unusual brain artery duplication is reported, highlighting the importance of advanced imaging in diagnosis.

## Contribution

The paper presents a unique anatomical case of PTA coexisting with a partial AComA duplication, emphasizing clinical implications.

## Key findings

- A persistent trigeminal artery was identified connecting the basilar artery to the left internal carotid artery.
- The anterior communicating artery showed partial duplication with two branches from the left anterior cerebral artery.
- The case underscores the need for 3D imaging in diagnosing rare cerebral artery variations.

## Abstract

Variations of the cerebral arterial circle are frequently observed due to the progressively increasing utilization of diagnostic imaging techniques. Among these variations, the persistence of embryonic vessels, such as the persistent trigeminal artery (PTA), is rare yet holds significant clinical relevance. This presentation details a distinctive case of the PTA coexisting with a partial duplication of the anterior communicating artery (AComA), as identified through magnetic resonance angiography (MRA) in a 41-year-old female patient. The PTA was documented as a vessel linking the basilar artery to the cavernous segment of the left internal carotid artery. The AComA exhibited two branches emanating from the left anterior cerebral artery (LACA), which fused to form a single vessel that anastomosed with the right anterior cerebral artery (RACA). The coexistence of the PTA and AComA variant accentuates the imperative for clinicians to consider such rare anatomical configurations, mainly when performing procedures in proximity to the gasserian ganglion, cavernous sinus, or anterior circulation. The application of three-dimensional imaging remains vital for ensuring precise diagnosis and effective treatment planning.

## Full-text entities

- **Diseases:** duplication (MESH:D058674)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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Source: https://tomesphere.com/paper/PMC12267363