# The Impact of Maternal/In Utero Exposure of Novel Tobacco Products on the Offspring Cardiovascular Health

**Authors:** Shelby S. Umphres, Precious O. Badejo, Fadi T. Khasawneh, Fatima Z. Alshbool

PMC · DOI: 10.1007/s12012-025-10023-5 · Cardiovascular Toxicology · 2025-06-20

## TL;DR

This paper reviews how exposure to new tobacco products during pregnancy may harm the cardiovascular health of children later in life.

## Contribution

It provides a comprehensive review of cardiovascular risks in offspring due to in utero exposure to novel tobacco products.

## Key findings

- Maternal use of novel tobacco products is linked to cardiovascular issues in offspring.
- Exposure during pregnancy may lead to long-term health consequences in children.
- Current evidence suggests these products are not safe alternatives during pregnancy.

## Abstract

Novel tobacco products (NTPs) have recently been on the rise appealing to a variety of users, including pregnant women and women of childbearing age, who deem these products to be a safe/safer alternative to traditional smoking. To this end, several studies have made advances toward proving the invalidity of these claims, especially in the context of cardiovascular disease. However, an area that has yet to be extensively explored is maternal/in utero exposure to these devices and the cardiovascular health outcomes on the offspring into their adult life. Herein, our aim is to critically assess the literature to identify and discuss the cardiovascular health risks that the offspring exhibits as a result of in utero exposure to NTPs. These studies have been summarized as a comprehensive review.

## Linked entities

- **Diseases:** cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** cardiovascular disease (MESH:D002318)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12267346/full.md

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Source: https://tomesphere.com/paper/PMC12267346