# High-resolution 3D whole-heart bright- and black-blood imaging with co-registered T2 mapping at 0.55 T

**Authors:** Ivan Kokhanovskyi, Carlos Castillo-Passi, Michael G. Crabb, Carl Ganter, Simon J. Littlewood, Karl P. Kunze, Dimitrios C. Karampinos, Marcus R. Makowski, Daniel Rueckert, Claudia Prieto, René M. Botnar

PMC · DOI: 10.3389/fcvm.2025.1572318 · Frontiers in Cardiovascular Medicine · 2025-07-03

## TL;DR

This paper introduces a new MRI technique that captures detailed heart images and tissue data in under 9 minutes using a lower magnetic field strength.

## Contribution

A novel 3D motion-compensated free-breathing MRI sequence for simultaneous bright- and black-blood imaging and co-registered T2 mapping at 0.55 T.

## Key findings

- The sequence provided clear delineation of cardiac and vascular structures in healthy subjects.
- Accurate T2 parametric mapping was achieved in less than 9 minutes.
- Good agreement with a spin-echo reference sequence was observed in phantom T2 mapping.

## Abstract

Conventional CMR exams for assessment of cardiac anatomy and tissue characterization require multiple sequential 2D acquisitions under breath-hold in different orientations, in addition to being limited to 1.5 T and 3 T.

In this study, we sought to develop a novel 3D motion-compensated free-breathing sequence for comprehensive high-resolution whole-heart assessment of cardiovascular anatomy via simultaneous bright- and black-blood imaging and co-registered T2 myocardial tissue quantification in a one-click scan at 0.55 T.

Good agreement with a spin-echo reference sequence was found in the phantom for T2 mapping. In-vivo, the proposed research sequence was evaluated in 10 healthy subjects, providing great delineation of cardiac and vascular structures, good visibility of coronary arteries and accurate T2 parametric mapping in a clinically feasible time of less than 9 min.

## Full-text entities

- **Chemicals:** T (MESH:D014316)

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12267252/full.md

## References

34 references — full list in the complete paper: https://tomesphere.com/paper/PMC12267252/full.md

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Source: https://tomesphere.com/paper/PMC12267252