# Factors affecting early and late period outcomes in patients undergoing surgical repair due to biliary tract injury

## TL;DR

This study examines factors affecting outcomes in patients who undergo surgery to repair biliary tract injuries following cholecystectomy.

## Contribution

The study identifies specific risk factors and outcomes associated with surgical repair of biliary tract injuries.

## Key findings

- Diabetes and culture positivity were linked to wound infections after surgery.
- Elevated ALP and GGT levels were associated with worse long-term outcomes.
- Anastomotic stricture occurred in 12.1% of patients, with some successfully treated via balloon dilation.

## Abstract

Cholecystectomy is the most common elective abdominal surgery globally. With the advent of laparoscopy, laparoscopic cholecystectomy has become the gold standard. However, this has also led to an increase in biliary tract injuries, a complication with high morbidity and mortality that requires a multidisciplinary treatment approach. This study aims to identify factors influencing postoperative outcomes in patients undergoing surgical repair for biliary tract injuries.

This study included 66 patients referred to the General Surgery Department of Çukurova University Medical Faculty for biliary tract injuries between January 2005 and June 2022, all of whom underwent hepaticojejunostomy. Demographic data, pre- and post-operative lab values, imaging, and anastomosis types were recorded and analyzed. Early and long-term postoperative outcomes were examined, using the McDonald classification for long-term follow-up.

Of the 66 patients, 18 (27.3%) were male, and 48 (72.7%) were female, with a mean follow-up of 105 ± 58 months. Early postoperative complications developed in 28 patients (42.4%). Diabetes and culture positivity were significantly associated with wound infections. Elevated pre- and post-repair ALP and GGT levels were significantly associated with poorer long-term outcomes according to the McDonald classification. Vascular injury was significantly associated with isolated ALP-GGT elevation. Anastomotic stricture developed in 8 patients (12.1%). Of these, 2 (3%) were successfully managed with balloon dilation

Biliary tract injury is a serious complication post-cholecystectomy, requiring a multidisciplinary approach and follow-up in a hepatobiliary center. Surgeon experience and local risk factors are crucial in managing these injuries.