# Early preeclampsia is associated with persistence of hypertension 3 months postpartum in women: an observational study at a tertiary hospital in Brazil

**Authors:** Gustavo Moleiro Tallarico, Priscila Oliveira Barbosa, Luiz Sérgio Lima-Junior, Ricardo Carvalho Cavalli

PMC · DOI: 10.61622/rbgo/2025rbgo38 · Revista Brasileira de Ginecologia e Obstetrícia · 2025-07-15

## TL;DR

This study found that women with early preeclampsia are more likely to have high blood pressure three months after giving birth, suggesting a need for longer monitoring.

## Contribution

The study identifies a link between early-onset preeclampsia and persistent postpartum hypertension in a Brazilian population.

## Key findings

- 62.5% of women with preeclampsia remained hypertensive three months postpartum.
- Early-onset preeclampsia was associated with a 2.36-fold increased risk of persistent hypertension.
- No significant differences in risk factors were found among participants with persistent hypertension.

## Abstract

This study aimed to investigate the persistence of hypertension at three months postpartum in women who experienced preeclampsia during pregnancy.

A prospective observational study at Hospital das Clínicas de Ribeirão Preto, Brazil, included 24 women. Blood pressure measurements and/or antihypertensive use were assessed, alongside risk factors such as body mass index (BMI), heart rate, lipid profile and C-reactive protein (CRP). Data on demographic, obstetric and lifestyle factors were also collected.

Out of 24 postpartum women enrolled in this study, 15 (62.5%) of participants remained hypertensive three months after delivery. Women with early-onset preeclampsia had a 2.36-fold increased risk of persistent hypertension at three months postpartum. No significant differences were found among risk factors for persistent hypertension.

Our results indicate a high prevalence of persistent hypertension in women with preeclampsia in Brazil. The findings highlight the need for extended monitoring specially in early onset preeclampsia and targeted lifestyle interventions.

## Linked entities

- **Diseases:** preeclampsia (MONDO:0005081)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** hypertension (MESH:D006973), preeclampsia (MESH:D011225)
- **Chemicals:** lipid (MESH:D008055)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12266848/full.md

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Source: https://tomesphere.com/paper/PMC12266848