# Spontaneous Perforated Uterine Pyometra Presenting With Abdominal Pain and Nausea

**Authors:** Xiu Zhang, Hao Bai, Tienan Feng

PMC · DOI: 10.7759/cureus.86129 · Cureus · 2025-06-16

## TL;DR

A 68-year-old postmenopausal woman died from septic shock after a rare uterine pyometra perforation was misdiagnosed as a gastrointestinal issue.

## Contribution

Highlights the importance of considering pyometra perforation in postmenopausal women with abdominal pain to improve outcomes.

## Key findings

- CT showed free gas and fluid in the abdomen, initially suggesting GI perforation.
- Laparotomy revealed pyometra perforation, but the patient died from septic shock.
- Timely diagnosis of pyometra is critical for postmenopausal women with abdominal pain.

## Abstract

Pyometra perforation is a rare and severe gynecological acute abdomen. If diagnosis and treatment are not timely, it can lead to septic shock and even endanger the patient's life. Here, we present a 68-year-old postmenopausal woman who presented with symptoms of upper abdominal pain accompanied by nausea. CT indicated a large amount of free gas in the abdominal cavity and fluid in the abdominal and pelvic cavities. Laparotomy was performed considering gastrointestinal (GI) perforation. During the operation, it was diagnosed as perforation of pyometra. After the operation, the patient was transferred to the intensive care unit and died of septic shock 13 hours after the operation. For postmenopausal women with abdominal pain, pyometra perforation should be taken into consideration. Correct identification and timely treatment are particularly crucial for the patient's prognosis.

## Linked entities

- **Diseases:** pyometra (MONDO:0000497)

## Full-text entities

- **Diseases:** Abdominal Pain (MESH:D015746), Nausea (MESH:D009325), Pyometra perforation (MESH:D055112), acute abdomen (MESH:D000006), perforation (MESH:D057112), septic shock (MESH:D012772), gastrointestinal (GI) perforation (MESH:D005767)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12265986/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12265986/full.md

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Source: https://tomesphere.com/paper/PMC12265986