# Spontaneous Pyometra in a Very Elderly Woman Revealing Serous Endometrial Carcinoma: A Case Report

**Authors:** Stefanos Flindris, Chrysoula Margioula-Siarkou, Georgia Margioula-Siarkou, Konstantinos Dinas, Stamatios Petousis

PMC · DOI: 10.7759/cureus.86137 · Cureus · 2025-06-16

## TL;DR

An 86-year-old woman with pyometra was found to have serous endometrial carcinoma, highlighting the need for prompt diagnosis and surgery in elderly patients.

## Contribution

This case report highlights the rare association of pyometra with serous endometrial carcinoma in an elderly patient.

## Key findings

- Pyometra in an elderly patient was found to be caused by serous endometrial adenocarcinoma confined to an endometrial polyp.
- Emergency laparotomy and histopathological evaluation were crucial for diagnosis and treatment.
- The patient remained disease-free after adjuvant radiotherapy and brachytherapy.

## Abstract

Pyometra is a rare accumulation of purulent material within the uterine cavity that most often arises in postmenopausal women with cervical stenosis. We report the case of an 86-year-old multiparous female patient with a history of multiple dilatation and curettage procedures who presented with a 15-day history of lower abdominal pain, spotting, and systemic signs of infection. Transvaginal ultrasound and contrast-enhanced CT confirmed a distended uterus filled with hypoechogenic fluid without evidence of perforation. Initial management with drainage under antibiotic coverage was complicated by paralytic ileus and rising inflammatory markers, prompting an emergency laparotomy. A total hysterectomy with bilateral salpingo-oophorectomy, appendectomy, and infracolic omentectomy was performed. Histopathology revealed a serous endometrial adenocarcinoma (International Federation of Gynecology and Obstetrics or FIGO stage IIC) confined to an endometrial polyp. Postoperatively, the patient recovered uneventfully, proceeded to adjuvant radiotherapy and brachytherapy because of occult malignancy, and remained disease-free at six months of follow-up. This case underscores the importance of early recognition and definitive surgical management of pyometra in elderly patients, as well as careful histopathologic evaluation to exclude underlying malignancy.

## Linked entities

- **Diseases:** pyometra (MONDO:0000497), serous endometrial adenocarcinoma (MONDO:0006196)

## Full-text entities

- **Diseases:** Endometrial Carcinoma (MESH:D016889), Pyometra (MESH:D055112), endometrial polyp (MESH:D014591), abdominal pain (MESH:D015746), infection (MESH:D007239), paralytic ileus (MESH:D007418), IIC (MESH:C565261), malignancy (MESH:D009369), cervical stenosis (MESH:D002575), inflammatory (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12265982/full.md

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Source: https://tomesphere.com/paper/PMC12265982