# Global, regional, and national burden of decubitus ulcers, 1990–2021: analysis of the current situation, multidimensional analysis, and trend forecasting for the global burden of disease study 2021

**Authors:** Zhaoyi Jing, Qingyu Song, Bingbing Wang, Xiao Ding, Wei Yan, Xianghua Qi

PMC · DOI: 10.3389/fmed.2025.1588032 · Frontiers in Medicine · 2025-07-02

## TL;DR

This study analyzed the global burden of decubitus ulcers from 1990 to 2021, finding increasing incidence and disparities, especially in low- and middle-income regions.

## Contribution

The study provides updated global, regional, and national estimates of decubitus ulcer burden and forecasts for 2035 using the GBD 2021 methodology.

## Key findings

- Incidence, prevalence, and mortality of decubitus ulcers increased globally from 1990 to 2021.
- India had the highest mortality and DALYs burden, while the U.S. had the highest incidence and prevalence.
- Population aging and growth were the main drivers of the rising disease burden.

## Abstract

This study aimed to deepen the understanding and assessment of the global burden of decubitus ulcers to provide evidence for policy making and resource allocation.

Using the standardized methodology of the 2021 Global Burden of Disease study, the disease burden of decubitus ulcers was analyzed at the global, regional, and national levels, with a focus on age and gender factors. The study also included health inequality analysis, decomposition analysis, and frontier analysis. The disease burden of decubitus ulcers for the year 2035 was projected.

From 1900 to 2021, the incidence, prevalence, and mortality of decubitus ulcers increased continuously. When analyzed by Socio-demographic Index (SDI), incidence decreased slightly in high-SDI regions but increased in all other regions. India was found to bear the heaviest burden of mortality and disability-adjusted life-years (DALYs), while the United States had the highest incidence and prevalence. Health inequality persisted, with the level of inequality in DALYs showing a greater increase compared to 1990. Decomposition analysis indicated that population aging and population growth remained the primary drivers of the increased burden of decubitus ulcers, with some regional variations. Frontier analysis revealed that countries positioned on the disease burden frontier were primarily located in middle-high and high SDI regions.

The burden of decubitus ulcers remains substantial globally, with marked disparities across regions and nations. A disproportionately high share of this burden affects older adult populations. Implementation of targeted health policies is warranted to mitigate the global burden of decubitus ulcers.

## Full-text entities

- **Diseases:** decubitus ulcers (MESH:D003668)

## Full text

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## Figures

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## References

41 references — full list in the complete paper: https://tomesphere.com/paper/PMC12263942/full.md

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Source: https://tomesphere.com/paper/PMC12263942