# The relationship between geochemical background values of MgO and SiO₂ and regional population longevity: evidence from Yunnan, China

**Authors:** Xin Zhou, Jiaxue Wang, Shuangshuang Zhu, Min Lai

PMC · DOI: 10.3389/fpubh.2025.1595130 · Frontiers in Public Health · 2025-07-02

## TL;DR

This study explores how natural levels of MgO and SiO₂ in Yunnan, China, relate to regional population longevity, finding that MgO is beneficial while high SiO₂ is harmful.

## Contribution

The study introduces a novel perspective linking geochemical background values to regional longevity using spatial and statistical analyses.

## Key findings

- MgO background values show a significant positive correlation with regional longevity indices.
- High SiO₂ background values are significantly negatively correlated with longevity measures.
- The Si/Mg ratio also negatively correlates with longevity, suggesting a detrimental effect of high SiO₂.

## Abstract

The relationship between geographical environments and human health has been a long-standing focus of scientific inquiry. Magnesium (Mg) and silicon (Si), as essential elements for the human body, play vital roles in individual health and may influence longevity. However, the extent to which the statistical characteristics of population longevity are associated with geochemical background values at a regional scale remains an important question.

This study examines Yunnan, China, a region with diverse and complex geographical conditions, and used global autocorrelation analysis, cluster and outlier analysis, and hotspot analysis to comprehensively analyze the Spatial Distribution Characteristics of magnesium oxide (MgO) and silicon dioxide (SiO₂) background values. It further investigates the individual and synergistic relationships of these geochemical factors with population longevity at the county scale in Yunnan using the Spearman rank correlation.

The results demonstrate that the MgO background value (ω(MgO)) exhibits a significant positive correlation with the Ultra-octogenarian Index and has a positive synergistic effect on regional longevity levels. In contrast, the SiO₂ background value (ω(SiO₂)) shows a significant negative correlation with both the longevity index and the Ultra-octogenarian Index, while the ratio of Si to Mg (ω(Si/Mg)) is also significantly negatively correlated with the Ultra-octogenarian Index.

These findings suggest that MgO-enriched natural environments may positively contribute to regional population longevity, while excessively high SiO₂ background values may have a detrimental effect. This study offers a novel perspective on the relationship between regional longevity levels and natural geographical environments, which may inform the selection and sustainable development of longevity-oriented tourism destinations.

## Full-text entities

- **Chemicals:** SiO2 (MESH:D012822), Si (MESH:D012825), MgO (MESH:D008277), Magnesium (MESH:D008274)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

54 references — full list in the complete paper: https://tomesphere.com/paper/PMC12263656/full.md

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Source: https://tomesphere.com/paper/PMC12263656