# Zero contrast technique in doubly committed subarterial ventricular septal defect closure in patient with body weight less than 10 kg: a case report

**Authors:** Radityo Prakoso, Rina Ariani, Aditya Agita Sembiring, Brian Mendel, Oktavia Lilyasari

PMC · DOI: 10.3389/fcvm.2025.1564232 · Frontiers in Cardiovascular Medicine · 2025-07-02

## TL;DR

This case report describes a successful zero-contrast transcatheter closure of a complex heart defect in a very young, low-weight patient.

## Contribution

The novelty lies in demonstrating the feasibility of zero-contrast closure for DCSA-VSD in a child under 10 kg.

## Key findings

- Zero-contrast transcatheter closure was successfully performed in a 9 kg patient with DCSA-VSD.
- The procedure resulted in complete defect closure with no residual shunt or valve dysfunction.
- The patient had no complications and showed excellent device positioning at follow-up.

## Abstract

The complex anatomy of DCSA VSD, its proximity to valvular and conduction tissues, and concerns about radiation and contrast make transcatheter closure particularly challenging in pediatric patients. While zero-fluoroscopy closure was not achievable in this case, we successfully performed zero-contrast transcatheter closure in a baby weighing less than 10 kg. This report highlights the feasibility and early outcomes of this approach at our institution.

An 18-month-old, 9 kg boy with a history of feeding difficulties, failure to thrive, and breathlessness since 14 days of age underwent transcatheter closure of a doubly committed subarterial (DCSA) ventricular septal defect (VSD). Transthoracic echocardiography revealed a 4–5 mm left-to-right shunting VSD with preserved ventricular function. Initial attempts to cross the VSD under zero-fluoroscopy guidance using various catheters were unsuccessful, necessitating fluoroscopic assistance without contrast. A Konar-MF VSD occluder (7/5 mm) was successfully deployed retrogradely, achieving complete defect closure with no residual shunt or valve dysfunction. Post-procedure, the patient remained asymptomatic, with excellent device positioning and no complications noted at follow-up.

This case demonstrates the feasibility of zero-contrast percutaneous DCSA-VSD closure in selected patients weighing less than 10 kg. Further studies are needed to validate its safety and long-term outcomes.

## Linked entities

- **Diseases:** ventricular septal defect (MONDO:0002070)

## Full-text entities

- **Diseases:** VSD (MESH:D006345), breathlessness (MESH:D004417), valve dysfunction (MESH:D006349), failure to thrive (MESH:D005183)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12263557/full.md

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Source: https://tomesphere.com/paper/PMC12263557