Laparoscopic Enbloc Gastric Resection of A Giant Gastrointestinal Stromal Tumor (GIST)
Sara Saeidi, Vincenzo Pappalardo, Andres Hanssen, Salomone Di Saverio

TL;DR
This paper discusses the successful use of minimally invasive surgery to remove a large stomach tumor, emphasizing the need for careful planning and follow-up to prevent recurrence.
Contribution
Demonstrates the feasibility of laparoscopic enbloc resection for large gastric GISTs in emergency scenarios.
Findings
Minimally invasive surgery is effective for large, bleeding gastric GISTs.
Careful surgical planning is crucial to avoid recurrence.
Ongoing monitoring is necessary due to the risk of GIST recurrence.
Abstract
Minimally invasive laparoscopic resection can be a feasible and effective option for managing large, bleeding gastric GISTs, even in emergency settings with organ adherence. Careful surgical planning and follow‐up are essential to prevent recurrence, as GISTs may reoccur, highlighting the importance of ongoing monitoring.
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Taxonomy
TopicsGastrointestinal Tumor Research and Treatment · Gastrointestinal disorders and treatments · Gastric Cancer Management and Outcomes
Gastrointestinal stromal tumors (GISTs) are common mesenchymal tumors of the digestive tract [1]. R0 resection is the preferred treatment for gastric GISTs [2], but the feasibility of laparoscopic resection in emergency cases involving large bleeding tumors with adherence is unclear. This report describes the laparoscopic enbloc resection of a giant GIST in a 69‐year‐old man who presented with gastrointestinal bleeding (Video S1).
The tumor, originating from the posterior gastric wall and adhering to the pancreas, was removed with free margins. The patient had no recurrence after 6 months. This case supports the efficacy of minimally invasive surgery for large, bleeding GISTs in emergencies.
Author Contributions
Sara Saeidi: conceptualization, data curation, formal analysis, investigation, methodology, writing – original draft, writing – review and editing. Vincenzo Pappalardo: conceptualization, data curation, formal analysis, investigation, writing – review and editing. Andres Hanssen: conceptualization, investigation, supervision, writing – original draft, writing – review and editing. Salomone Di Saverio: conceptualization, data curation, investigation, supervision, validation, writing – review and editing.
Consent
Written informed consent was obtained from our patient who is included in the video vignette.
Conflicts of Interest
The authors declare no conflicts of interest.
Supporting information
Video S1. Laparoscopic enbloc resection of a giant bleeding gastrointestinal stromal tumor (GIST). The video demonstrates key steps of the minimally invasive procedure, including tumor dissection, resection from adjacent organs, and final specimen extraction. This technique highlights the feasibility of laparoscopic management for large bleeding GISTs in an emergency setting.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1M. Miettinen and J. Lasota , “Gastrointestinal Stromal Tumors,” Gastroenterology Clinics of North America 42, no. 2 (2013): 399–415.23639648 10.1016/j.gtc.2013.01.001PMC 3644178 · doi ↗ · pubmed ↗
- 2G. Pantuso , I. Macaione , A. Taverna , et al., “Surgical Treatment of Primary Gastrointestinal Stromal Tumors (GIS Ts): Management and Prognostic Role of R 1 Resections,” American Journal of Surgery 220, no. 2 (2020): 359–364.31862107 10.1016/j.amjsurg.2019.12.006 · doi ↗ · pubmed ↗
