# Selective Laser Trabeculoplasty Versus Pattern Scanning Laser Trabeculoplasty for Reducing Intraocular Pressure in Primary Open-Angle Glaucoma

**Authors:** Jonathan Remon, Jessica M Diesing, Andrew J Boileau

PMC · DOI: 10.7759/cureus.86050 · Cureus · 2025-06-15

## TL;DR

This study compares two laser treatments for glaucoma and finds they both lower eye pressure effectively, though one may be more comfortable.

## Contribution

The paper provides a comparative analysis of SLT and PSLT for IOP reduction in POAG, highlighting their similar efficacy and tolerability differences.

## Key findings

- SLT and PSLT both effectively reduce intraocular pressure in primary open-angle glaucoma patients.
- PSLT may cause slightly greater short-term IOP reduction and is reported as more tolerable by patients.
- Both treatments are equally efficacious, but more research is needed on long-term effects and mechanisms.

## Abstract

Selective laser trabeculoplasty (SLT) significantly lowers the intraocular pressure (IOP) in open-angle glaucoma patients compared to pattern scanning laser trabeculoplasty (PSLT). This review contains results from randomized control trials and a retrospective database analysis obtained through PubMed and Google Scholar. PubMed searches used the following words and terms: "selective laser trabeculoplasty" AND "pattern scanning trabeculoplasty.” A similar search on Google Scholar eventually uncovered one additional study comparing the two trabeculoplasty methods. All studies included patients diagnosed with primary open-angle glaucoma (POAG) or ocular hypertension.

SLT has not consistently shown superiority over PSLT in managing POAG. PSLT may result in slightly greater short-term reductions in IOP. Patients often report less discomfort with this method, suggesting it may be more tolerable. Both treatments can lead to meaningful reductions in IOP from baseline, which is generally considered a positive treatment outcome.

SLT and PSLT were shown to exert the same efficacy. In terms of treatment, both procedures are efficient and beneficial for lowering IOP. PSLT was favored to be more tolerable in one of the studies. Further research is required to observe potential side effects, long-term treatment, and mechanisms of action of both lasers.

## Linked entities

- **Diseases:** primary open-angle glaucoma (MONDO:0005338), ocular hypertension (MONDO:0006875)

## Full-text entities

- **Diseases:** ocular hypertension (MESH:D009798), POAG (MESH:D005902)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12263457/full.md

## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12263457/full.md

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Source: https://tomesphere.com/paper/PMC12263457