# Bilateral Idiopathic Multifocal Retinal Pigment Epithelial Detachments: A Case Report and Brief Review of the Literature

**Authors:** Dimitrios Kalogeropoulos, Ahmed Ibraheem, Daniel Dragnev

PMC · DOI: 10.7759/cureus.86048 · 2025-06-15

## TL;DR

This paper presents a rare case of multiple retinal pigment epithelial detachments in a healthy person with no underlying condition.

## Contribution

The novelty lies in reporting a rare case of idiopathic multifocal retinal pigment epithelial detachments in an asymptomatic individual.

## Key findings

- Idiopathic retinal pigment epithelial detachments are extremely rare and often occur without symptoms.
- Comprehensive clinical examination and multimodal imaging are essential for accurate diagnosis.
- The case highlights the importance of ruling out systemic conditions in similar presentations.

## Abstract

Retinal pigment epithelial detachments (PEDs) result from a disruption at the junction between the basement membrane of the retinal pigment epithelium (RPE) and the innermost part of Bruch’s membrane. Serous retinal PEDs, whether singular or multiple, are frequently seen across a broad spectrum of ophthalmic disorders. Additionally, PEDs have been associated with various systemic conditions, including renal, hypertensive, endocrine, and hematologic disorders. Idiopathic PEDs, which occur without an associated underlying condition, are exceedingly rare, with only a few cases reported in the literature. Herein, we report a case of an asymptomatic and otherwise healthy individual with multiple idiopathic retinal PEDs, highlighting the importance of a comprehensive clinical examination and multimodal ophthalmic imaging.

## Full-text entities

- **Diseases:** renal, hypertensive, endocrine, and hematologic disorders (MESH:D006977), ophthalmic disorders (MESH:C535922), retinal (MESH:D012173), Idiopathic PEDs (MESH:D012163)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12261811/full.md

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Source: https://tomesphere.com/paper/PMC12261811