# Recurrent Systemic Embolization in a Patient With Aortic Valve Amyloidosis

**Authors:** Annalisa Caputo, Amedeo Pergolini, Luigi Monticelli, Enrico Natale, Antonio Lio, Maria Cristina Macciomei, Giulia D'Amati, Martina Leopizzi, Carla Manzara

PMC · DOI: 10.1111/echo.70241 · 2025-07-15

## TL;DR

A 47-year-old woman experienced multiple blood clots due to a rare condition involving aortic valve amyloidosis and antiphospholipid syndrome.

## Contribution

Highlights a rare case of isolated aortic valve amyloidosis causing recurrent thromboembolic events in the context of antiphospholipid syndrome.

## Key findings

- The patient had recurrent thromboembolic events including STEMI and limb ischemia.
- Aortic valve thrombosis was caused by isolated aortic valve amyloidosis.
- The condition occurred alongside antiphospholipid syndrome.

## Abstract

A rare case of a 47‐year‐old woman with recurrent thromboembolic events, including STEMI and lower limb ischemia, diagnosed with aortic valve thrombosis caused by isolated aortic valve amyloidosis in the setting of overlapping antiphospholipid syndrome.

## Linked entities

- **Diseases:** antiphospholipid syndrome (MONDO:0017278), STEMI (MONDO:0041656)

## Full-text entities

- **Diseases:** antiphospholipid syndrome (MESH:D016736), thromboembolic (MESH:D013923), STEMI (MESH:D000072657), Aortic Valve Amyloidosis (MESH:D001024), lower limb ischemia (MESH:D007511)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12260778/full.md

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Source: https://tomesphere.com/paper/PMC12260778