# Therapeutic Efficacy of Platelet-Rich Fibrin in Delayed Replantation of an Avulsed Tooth: A Clinical Case Report on Management and Outcome Assessment

**Authors:** Akansha Tilokani, Yash Sinha, Prasanti Pradhan, Sonali Bansal, Aditi Gupta

PMC · DOI: 10.7759/cureus.86029 · Cureus · 2025-06-14

## TL;DR

This case report shows how platelet-rich fibrin helped successfully replant a tooth after it was out of the mouth for over an hour.

## Contribution

Demonstrates the novel use of platelet-rich fibrin in managing delayed tooth replantation with prolonged dry time.

## Key findings

- The replanted tooth remained asymptomatic and stable for two years.
- No signs of resorption or infection were observed during follow-up.
- PRF contributed to successful healing in a challenging dental trauma case.

## Abstract

This case report describes the successful management of a delayed replantation of an avulsed maxillary central incisor with prolonged extraoral dry time (>60 minutes). A 24-year-old patient presented with a dehydrated avulsed tooth, which underwent extraoral root canal treatment and replantation using platelet-rich fibrin (PRF) to enhance healing. The tooth was splinted for four weeks, and the patient was followed up for two years. The replanted tooth remained asymptomatic, stable, and showed no signs of resorption or infection. This case highlights the importance of a multidisciplinary approach, integrating advanced biological and clinical techniques, in achieving favourable outcomes in traumatic dental injuries.

## Full-text entities

- **Diseases:** infection (MESH:D007239), traumatic dental injuries (MESH:D014947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12260252/full.md

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Source: https://tomesphere.com/paper/PMC12260252