# The coming of age of DNA‐based catalysts for therapeutic applications

**Authors:** Robert Hesse, Christoph G. W. Gertzen, Jessica Felice Schmuck, Justin Darvin Böcker, Piyush Pandey, Tobias Behn, Christopher Ruth, Detlev Riesner, Stephanie Kath‐Schorr, Philipp A. Lang, Holger Gohlke, Manuel Etzkorn

PMC · DOI: 10.1002/ctm2.70408 · Clinical and Translational Medicine · 2025-07-14

## Full-text entities

- **Genes:** SOCS3 (suppressor of cytokine signaling 3) [NCBI Gene 9021] {aka ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3}, PDLIM7 (PDZ and LIM domain 7) [NCBI Gene 9260] {aka LMP1, LMP3}, JUN (Jun proto-oncogene, AP-1 transcription factor subunit) [NCBI Gene 3725] {aka AP-1, AP1, c-Jun, cJUN, p39}, GATA3 (GATA binding protein 3) [NCBI Gene 2625] {aka HDR, HDRS}, DAXX (death domain associated protein) [NCBI Gene 1616] {aka BING2, DAP6, EAP1}
- **Diseases:** rare diseases (MESH:D035583), viral (MESH:D014777), infection (MESH:D007239), COVID-19 (MESH:D000086382), toxicity (MESH:D064420), bacterial infections (MESH:D001424), allergic (MESH:D004342), atopic eczema (MESH:D003876), BCC (MESH:D002280), ulcerative colitis (MESH:D003093), NPC (MESH:D000077274), inflammatory (MESH:D007249), Japanese encephalitis virus infection (MESH:D004672), neurodegeneration (MESH:D019636), asthmatic (MESH:D013224), cancer (MESH:D009369), asthma (MESH:D001249)
- **Chemicals:** 6-thio-G14 (-), ASO (MESH:D016376), metal (MESH:D008670), sugar (MESH:D000073893), nucleotides (MESH:D009711), oligonucleotides (MESH:D009841)
- **Species:** Respiratory syncytial virus (no rank) [taxon 12814], human gammaherpesvirus 4 (Epstein Barr virus, no rank) [taxon 10376], Homo sapiens (human, species) [taxon 9606], Influenza A virus (no rank) [taxon 11320], Japanese encephalitis virus (no rank) [taxon 11072], Mus musculus (house mouse, species) [taxon 10090], Enterovirus (genus) [taxon 12059], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049]
- **Cell lines:** Hep-2 — Homo sapiens (Human), Human papillomavirus-related endocervical adenocarcinoma, Cancer cell line (CVCL_1906)

## Full text

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12260117/full.md

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Source: https://tomesphere.com/paper/PMC12260117