# Primary hepatic leiomyosarcoma concurrent with early-stage lung adenocarcinoma: a rare case report

## TL;DR

A rare case of primary hepatic leiomyosarcoma occurring alongside early-stage lung cancer is reported, emphasizing the need for thorough diagnostics and multidisciplinary care.

## Contribution

This is the first reported case of primary hepatic leiomyosarcoma concurrent with primary lung adenocarcinoma.

## Key findings

- A 46-year-old female had a hepatic mass and a pulmonary nodule confirmed as primary hepatic leiomyosarcoma and lung adenocarcinoma.
- The case underscores the importance of comprehensive diagnostics and multidisciplinary management in rare hepatic tumors.
- This case provides insights into managing patients with concurrent rare hepatic and pulmonary malignancies.

## Abstract

Primary hepatic leiomyosarcoma (PHL) is an extremely rare malignant mesenchymal tumor, accounting for less than 2% of all primary hepatic malignancies. We report a case of a 46-year-old female who presented with a one-year history of abdominal distension and pain. Imaging revealed a 6×5×4 cm mass in the left hepatic lobe (segments 3/4) and incidentally detected a suspicious pulmonary nodule. Laparoscopic partial left hepatectomy followed by thoracoscopic wedge resection of the left upper lung confirmed the diagnoses of primary hepatic leiomyosarcoma and primary lung adenocarcinoma (cT1aN0M0), respectively. This case highlights the importance of comprehensive diagnostics, immunohistochemical analysis, and multidisciplinary management of rare hepatic tumors, particularly when concurrent malignancies are present. This first reported case of concurrent PHL and primary lung adenocarcinoma provides valuable insights for clinical practice in managing patients with rare hepatic malignancies.