# Unmasking the Silent Culprit: Gastric Neuroendocrine Tumor in the Setting of Iron Deficiency Anemia

**Authors:** Ashley Serjilus, Sarah K Zimmer, Allison M Bush, Javier N De Luca-Johnson, Bryan J Keenan, Amie L Harvey

PMC · DOI: 10.7759/cureus.86010 · Cureus · 2025-06-14

## TL;DR

This paper discusses a rare case of a gastric neuroendocrine tumor discovered in a young woman with long-term iron deficiency anemia.

## Contribution

The novelty lies in highlighting a rare subtype (type 3) of gastric neuroendocrine tumor presenting as iron deficiency anemia.

## Key findings

- A young female with long-standing iron deficiency and menorrhagia was diagnosed with a type 3 gastric neuroendocrine tumor.
- Gastric neuroendocrine tumors can present with nonspecific symptoms like iron deficiency anemia.
- Iron deficiency in menstruating individuals is often overlooked as a sign of gastrointestinal tumors.

## Abstract

Gastric neuroendocrine tumors (GNETs) are uncommon neoplasms; it is classified into four subtypes based on low to high risk of progression and developing metastasis. GNETs can be asymptomatic or present with nonspecific signs and symptoms, including dyspepsia and iron deficiency anemia (IDA). In people who menstruate, iron deficiency is often attributed to menstrual cycles, and they may not undergo investigation for gastrointestinal sources. We present a case of a young female with long-standing iron deficiency and menorrhagia, who was found to have a rare GNET, most consistent with a type 3 subset.

## Linked entities

- **Diseases:** gastric neuroendocrine tumor (MONDO:0015062), iron deficiency anemia (MONDO:0001356)

## Full-text entities

- **Diseases:** neoplasms (MESH:D009369), dyspepsia (MESH:D004415), GNETs (MESH:D018358), iron deficiency (MESH:D000090463), metastasis (MESH:D009362), menorrhagia (MESH:D008595), IDA (MESH:D018798)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12258610/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12258610/full.md

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Source: https://tomesphere.com/paper/PMC12258610