# P21 Healthcare students’ knowledge of antibiotic ineffectiveness in treating viral infections: a systematic review and meta-analysis

## TL;DR

This study finds that while most healthcare students know antibiotics don't work on viruses, significant gaps remain, especially in some countries.

## Contribution

The study provides global and regional estimates of healthcare students' knowledge about antibiotic ineffectiveness against viral infections.

## Key findings

- 70.2% of healthcare students correctly understood antibiotics are ineffective against viruses.
- Only 58.0% knew antibiotics don't work on colds and flu.
- Countries like Thailand and Turkey showed notably lower knowledge levels compared to the US and UK.

## Abstract

The overuse of antibiotics by healthcare professionals is often associated with a lack of knowledge regarding the rational use of these medications. We synthesized and analysed existing evidence on healthcare students' knowledge of antibiotic ineffectiveness in treating viral infections to provide pooled global and regional estimates.

The PubMed®, Embase® (via Ovid) and CINAHL (via EBSCO) databases were systematically searched for studies published between 01 January 2014 and 31 December 2024 that reported Healthcare students’ knowledge of antibiotic ineffectiveness in treating viral infections. Pooled estimates and 95% CI of correct knowledge were determined using random-effects meta-analysis.

Of the 9165 articles identified, 86 studies met the inclusion criteria. Most healthcare students correctly understood that antibiotics are ineffective against viruses, with 70.2% (95% CI: 65.6–74.8) demonstrating this understanding. Only 58.0% (95% CI: 51.4–64.6) knew that antibiotics are ineffective against colds and flu. There were no significant regional variations in the understanding that antibiotics are ineffective against viruses. However, notable differences were evident at the country level. Thailand (30.3%, 95CI: 23.8–37.8), Turkey (35.8%, 95% CI: 32.9–38.8), Mali (39.9%, 95% CI: 35.5–44.5), and China (45.7%, 95% CI: 43.5–47.9) demonstrated lower levels of knowledge, whereas Poland (94.0%, 95% CI: 90.4–97.5), the United States (98.0%, 95% CI: 94.5–99.3), and the United Kingdom (98.4%, 95% CI: 97.2–99.6) exhibited higher levels of understanding.

Our findings indicate significant knowledge gaps in the understanding of the ineffectiveness of antibiotics against viruses in many countries. These knowledge gaps have important implications for the rational use of antibiotics and the prevention of resistance.

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Source: https://tomesphere.com/paper/PMC12258457