# Apple Cider Vinegar-Induced Hepatotoxicity: A Rare Case Report

**Authors:** Celina R Andonie, Saja I AbuGhannam, Shadi M A Ruzayqat

PMC · DOI: 10.1093/omcr/omaf097 · 2025-07-14

## TL;DR

A 60-year-old man developed liver damage from long-term apple cider vinegar use, highlighting its potential hepatotoxic effects.

## Contribution

Reports a rare case linking apple cider vinegar to idiosyncratic liver damage in humans.

## Key findings

- A 60-year-old man experienced hepatotoxicity linked to long-term apple cider vinegar consumption.
- Discontinuation of vinegar use led to improvement in the patient's condition.
- The case suggests vinegar should be considered as a potential cause of liver damage.

## Abstract

Apple cider vinegar is a ubiquitous ingredient that has been used for many years. There are not many reports in the literature of idiosyncratic drug-induced liver damage linked to apple cider vinegar in people. As far as we are aware, liver damage is an uncommon side effect of long-term apple cider vinegar use. We describe the case of a 60-year-old man who had a long history of vinegar consumption and now had vinegar-induced hepatotoxicity. After the patient stopped using vinegar, his condition improved. This case emphasizes how important it is to take into account conventional substances like vinegar as possible causes of liver damage.

## Full-text entities

- **Diseases:** liver damage (MESH:D056486)
- **Chemicals:** Vinegar (MESH:D019342)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12258026/full.md

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Source: https://tomesphere.com/paper/PMC12258026