# Locally advanced port-site metastasis following laparoscopic surgery for early-stage endometrial carcinoma: a case report

**Authors:** Sabrillah Echiguer, Soumaya Elgraini, Yassine El Bouazizi, Fatima Zahra Belkouchi, Fouad Tijami, Youssef Omor, Rachida Latib, Hafid Hachi, Nezha El Bahaoui

PMC · DOI: 10.1093/jscr/rjaf509 · 2025-07-14

## TL;DR

A rare case of port-site metastasis after laparoscopic endometrial cancer surgery is reported, highlighting the need for early detection and multidisciplinary treatment.

## Contribution

This case report provides insights into managing a rare complication of laparoscopic surgery for endometrial cancer.

## Key findings

- A 66-year-old patient developed locally advanced port-site metastasis 18 months after laparoscopic surgery.
- Neoadjuvant chemotherapy enabled complete surgical resection of the metastatic mass.
- Early recognition and multidisciplinary care are critical for managing port-site metastasis.

## Abstract

Port-site metastasis (PSM) following minimally invasive surgery for early-stage endometrial cancer is rare, and its underlying pathophysiology remains poorly understood. Currently, no standardized treatment protocol exists. We report the case of a 66-year-old woman who developed a locally advanced PSM 18 months after undergoing laparoscopic surgery for early-stage endometrioid adenocarcinoma. She was treated with neoadjuvant chemotherapy to reduce the mass and enable complete surgical resection. Although the incidence of PSM is low, its management poses significant clinical challenges and can be associated with a poor prognosis. Early recognition, an adapted multidisciplinary approach, and implementation of preventive strategies during initial surgery are critical to optimizing outcomes.

## Linked entities

- **Diseases:** endometrial carcinoma (MONDO:0002447), endometrioid adenocarcinoma (MONDO:0005026)

## Full-text entities

- **Diseases:** endometrial cancer (MESH:D016889), endometrioid adenocarcinoma (MESH:D018269), PSM (MESH:D009362)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12257627/full.md

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Source: https://tomesphere.com/paper/PMC12257627