# An open-source, automated machine learning approach for large-scale image retrieval for thoracic aorta analysis studies

**Authors:** Brian C Ayers, Aaron D Aguirre, Thoralf M Sundt, Michael T Lu, Arminder Jassar

PMC · DOI: 10.1093/jamiaopen/ooaf066 · 2025-07-14

## TL;DR

This paper introduces an open-source automated system to accurately find specific thoracic aorta CT scans from a large and varied database.

## Contribution

The novel contribution is an open-source, high-accuracy image retrieval pipeline for thoracic aorta CT scans.

## Key findings

- The pipeline identified 82% of relevant scans with 99.1% accuracy.
- Excluded scans were correctly rejected in 93.6% of cases.

## Abstract

To develop an image retrieval pipeline capable of identifying specific series of thoracic aortic computed tomography (CT) scans from a diverse database.

An automated image analysis pipeline was developed to select series that show the entire thoracic aorta with arterial phase contrast from within a heterogeneous institutional cohort of 4184 CT scans of the chest.

The automated pipeline identified 3435 (82%) studies from within the database that met criteria. Manual review confirmed 99.1% of the selected scans were accurately selected, and 93.6% of excluded scans were appropriately excluded.

We present an open-source, image-retrieval pipeline that, with a high degree of accuracy, can identify aortic imaging studies that meet specific criteria from within a heterogeneous collection of images. This pipeline serves as a framework that can be easily modified for other clinical use cases and can be deployed across multiple centers to promote multi-institutional research.

## Full-text entities

- **Diseases:** thrombus (MESH:D013927), TAA (MESH:D017545), CT (MESH:C000719218), aneurysm (MESH:D000783), aortic aneurysm or dissection (MESH:D000784), aortic complications (MESH:D008107)
- **Chemicals:** HU (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12257624/full.md

---
Source: https://tomesphere.com/paper/PMC12257624