# Correction: Hybrid thiazolyl–benzylidene–phenol metal complexes as novel chemotherapeutic agents with anti-topoisomerase I activity in human breast carcinoma: synthesis, in vitro and in silico studies

**Authors:** Ahmed M. Alharbi, Mona Katary, Khulud M. Alshehri, Basim H. Asghar, Mohmed M. Omran, Reda F. M. Elshaarawy, Amira Mili, Hani S. Hafez, Rozan Zakaria

PMC · DOI: 10.1039/d5ra90086g · 2025-07-14

## TL;DR

This paper corrects a previous study on new metal complexes that may help treat breast cancer by targeting an enzyme involved in DNA repair.

## Contribution

The paper provides a correction to prior research on the synthesis and testing of novel metal complexes for breast cancer treatment.

## Key findings

- The corrected study details the synthesis of hybrid thiazolyl–benzylidene–phenol metal complexes.
- These complexes show anti-topoisomerase I activity, which is relevant for cancer therapy.
- In vitro and in silico studies support their potential as chemotherapeutic agents.

## Abstract

Correction for ‘Hybrid thiazolyl–benzylidene–phenol metal complexes as novel chemotherapeutic agents with anti-topoisomerase I activity in human breast carcinoma: synthesis, in vitro and in silico studies’ by Ahmed M. Alharbi et al., RSC Adv., 2025, 15, 20552–20569, https://doi.org/10.1039/D5RA00889A.

## Linked entities

- **Proteins:** Top1 (Topoisomerase 1)
- **Diseases:** breast cancer (MONDO:0004989)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** breast carcinoma (MESH:D001943)
- **Chemicals:** thiazolyl-benzylidene-phenol metal (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12257288