# Bioresorbable hyaluronic acid alginate hydrogel use in total ankle arthroplasty to control post-operative scarring

**Authors:** Jay S Badell

PMC · DOI: 10.1093/jscr/rjaf533 · 2025-07-14

## TL;DR

This study explores using a hyaluronic acid alginate hydrogel during ankle replacement surgery to reduce scarring and improve patient outcomes.

## Contribution

The novel use of a hyaluronic acid alginate hydrogel during surgery to prevent post-operative scarring is introduced.

## Key findings

- Using the hydrogel at the time of surgery may decrease the risk of peri-prosthetic scarring.
- Improved joint range of motion and patient satisfaction are potential benefits of this approach.

## Abstract

End-stage ankle arthritis can be a debilitating condition, with ankle replacement as an avenue for significant pain relief and functional return to activity. However, peri-prosthetic scarring and ectopic bone formation are commonly observed following joint replacement surgery, and several methods of treatment exist to address these conditions post-operatively, with varied success. Maintenance of ankle joint range of motion has been shown to lead to lower pain and higher patient satisfaction following ankle replacement. Presented in this study is the use of a hyaluronic acid alginate hydrogel at the time of index surgery to decrease the risk of peri-prosthetic scarring.

## Full-text entities

- **Diseases:** bone (MESH:D001847), pain (MESH:D010146), ankle arthritis (MESH:D001168)
- **Chemicals:** hyaluronic acid alginate (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12257093/full.md

---
Source: https://tomesphere.com/paper/PMC12257093