# Ovarian Sertoli-Leydig Tumour in a Postmenopausal Female With Virilisation: Magnetic Resonance Imaging Findings

**Authors:** Yuya Yamamoto, Iichiro Osawa, Masao Takahashi, Kosei Hasegawa, Masanori Yasuda

PMC · DOI: 10.7759/cureus.85965 · 2025-06-13

## TL;DR

This paper presents an MRI case study of a rare ovarian tumor in a postmenopausal woman that caused virilization.

## Contribution

The study highlights the MRI characteristics of Sertoli-Leydig cell tumors in a postmenopausal patient with hormonal changes.

## Key findings

- The tumor showed high signal intensity in early and delayed MRI phases.
- The uterine myometrium had high signal intensity with a clear junctional zone on T2-weighted images.
- The patient had an enlarged clitoris and elevated androgen and estrogen levels.

## Abstract

Sertoli-Leydig cell tumours (SLCTs) of the ovary are uncommon sex cord-stromal tumours that may cause virilisation and menometrorrhagia. Herein, we describe the magnetic resonance imaging features of SLCT in a 75-year-old female who exhibited virilisation with elevated androgen and oestrogen levels. The tumour appeared as a well-defined multilobulated mass. Measuring 8 cm in diameter with flow voids and cavitation, and showed high signal intensity in the early and delayed phases. The uterine myometrium showed high signal intensity and a clear junctional zone on T2-weighted images, and the clitoris was enlarged. A solid ovarian mass demonstrating intense enhancement with flow voids associated with elevated oestrogen levels and virilisation could suggest SLCT.

## Full-text entities

- **Diseases:** sex cord-stromal tumours (MESH:D018312), Ovarian Sertoli-Leydig Tumour (MESH:D010051), SLCTs (MESH:D018310), tumour (MESH:D009369)

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12256710/full.md

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Source: https://tomesphere.com/paper/PMC12256710