# Meckel's diverticulum as a lead point for intussusception in the first day of life: A case report of neonatal perforation

**Authors:** Usama Qumsieh, Alaa R. Al-Ihribat, Shahd B. Shawar, Ahmed J.M. Doudin, Omar A. Alhroub, Omar Y.A. Hajjaj

PMC · DOI: 10.1016/j.ijscr.2025.111548 · International Journal of Surgery Case Reports · 2025-06-19

## TL;DR

A full-term newborn developed a rare case of intussusception caused by Meckel's diverticulum within 24 hours of birth, leading to bowel perforation and requiring emergency surgery.

## Contribution

This is one of the earliest reported cases of Meckel's diverticulum causing intussusception and perforation in a term neonate.

## Key findings

- Meckel's diverticulum acted as a lead point for ileoileal intussusception in a 13-hour-old neonate.
- The case highlights the importance of considering intussusception in neonates with abdominal distension and pneumoperitoneum.
- Prompt surgical intervention was critical for the neonate's recovery despite intraoperative complications.

## Abstract

Intussusception in neonates is extremely rare, especially in full-term newborns. Even rarer is the occurrence of Meckel's diverticulum (MD) acting as a lead point within the first 24 h of life. Prompt recognition is critical as delays can lead to bowel perforation and life-threatening complications.

We report a case of a 13-hour-old full-term female neonate who presented with abdominal distension and signs of sepsis shortly after her first feed. Imaging revealed pneumoperitoneum, prompting emergent laparotomy. Intraoperatively, ileoileal intussusception with bowel perforation was identified, with Meckel's diverticulum acting as the lead point. The affected segment was resected with primary anastomosis. The patient required cardiopulmonary resuscitation intraoperatively but eventually made a full recovery after a second-look surgery and NICU support.

This case represents one of the earliest presentations of MD-related intussusception complicated by bowel perforation in a term neonate. Diagnosing intussusception in neonates is challenging due to atypical presentation. Although MD is the most common congenital GI anomaly, it rarely presents symptomatically in neonates, let alone as a cause of intussusception and perforation on day one of life.

Neonatal intussusception, particularly in term infants, should not be overlooked in the differential diagnosis of early abdominal emergencies. Meckel's diverticulum, despite its rarity as a lead point in this age group, must be considered to avoid delayed diagnosis and serious complications.

•Neonatal intussusception is a rare cause of bowel obstruction in full-term neonates.•Meckel’s diverticulum may act as a lead point for intussusception in the first 24 hours.•Abdominal distension and pneumoperitoneum needs urgent surgical evaluation in neonates.•Consider intussusception and Meckel’s diverticulum in neonatal abdominal emergency diagnosis.

Neonatal intussusception is a rare cause of bowel obstruction in full-term neonates.

Meckel’s diverticulum may act as a lead point for intussusception in the first 24 hours.

Abdominal distension and pneumoperitoneum needs urgent surgical evaluation in neonates.

Consider intussusception and Meckel’s diverticulum in neonatal abdominal emergency diagnosis.

## Linked entities

- **Diseases:** intussusception (MONDO:0007835), bowel perforation (MONDO:0006807)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** bowel perforation (MESH:D057112), sepsis (MESH:D018805), Intussusception (MESH:D007443), congenital GI anomaly (MESH:D000013), abdominal distension (MESH:D000007), pneumoperitoneum (MESH:D011027), MD (MESH:D008467)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12256289/full.md

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Source: https://tomesphere.com/paper/PMC12256289