# Necrotizing Soft Tissue Infection Secondary to Spinal Hardware Malfunction: A Case Report on Surgical Debridement

**Authors:** Patrick D Plummer, Landry Umbu, Penelope Mashburn, Ryan Debiec

PMC · DOI: 10.7759/cureus.85917 · Cureus · 2025-06-13

## TL;DR

A 54-year-old woman with diabetes and malfunctioning spinal hardware developed a severe flesh-eating infection requiring urgent surgery.

## Contribution

This case report highlights an unusual cause of necrotizing soft tissue infection linked to spinal hardware malfunction.

## Key findings

- The patient developed a necrotizing soft tissue infection while in the ICU.
- Surgical debridement was required to manage the aggressive infection.
- The patient's medical history included diabetes and spinal surgery with hardware issues.

## Abstract

Necrotizing soft tissue infections (NSTIs) are characterized by “flesh-eating bacteria” that are rapidly progressive and require immediate diagnosis and aggressive surgical debridement along with broad-spectrum antibiotics. Common pathogens, such as Streptococcus pyogenes, Staphylococcus aureus, Enterococcus coli, and Clostridium, are the usual culprits of this disease. While NSTIs have a relatively low incidence, they are associated with higher rates of morbidity and mortality. Due to the aggressive nature of the pathogen, NSTI can cause widespread necrosis of soft tissue and muscle, leading to extensive surgical intervention and patient disfigurement. The patient population that is most susceptible to NSTI includes the elderly, immunocompromised, and diabetics. In this case report, the patient is a 54-year-old woman with a past medical history of type 2 diabetes mellitus, hepatitis C, and an extensive spinal surgery with malfunctioning spinal hardware who developed an NSTI while in the intensive care unit.

## Linked entities

- **Diseases:** necrotizing soft tissue infection (MONDO:0018602), type 2 diabetes mellitus (MONDO:0005148)

## Full-text entities

- **Diseases:** necrosis (MESH:D009336), NSTIs (MESH:D018461), type 2 diabetes mellitus (MESH:D003924), Infection (MESH:D007239), hepatitis C (MESH:D019698), diabetics (MESH:D003920)
- **Species:** Escherichia coli (E. coli, species) [taxon 562], Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Homo sapiens (human, species) [taxon 9606], Streptococcus pyogenes (species) [taxon 1314], Clostridium (genus) [taxon 1485], Staphylococcus aureus (species) [taxon 1280]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12256013/full.md

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Source: https://tomesphere.com/paper/PMC12256013