# A Rare Case of Biliary Cast Syndrome After Orthotopic Liver Transplantation

**Authors:** Abdelrhman Refaey, Ahmed Attia, Ahmed Ebeid, Stephen Gray, Ameer Abutaleb

PMC · DOI: 10.7759/cureus.85883 · Cureus · 2025-06-12

## TL;DR

This paper reports a rare case of biliary cast syndrome in a liver transplant patient, emphasizing the importance of early diagnosis and treatment.

## Contribution

The paper presents a rare clinical case of biliary cast syndrome following liver transplantation.

## Key findings

- A 48-year-old woman developed biliary cast syndrome nine weeks after liver transplantation.
- The patient experienced complications including biloma, anemia, and septic shock.
- Endoscopic removal of biliary casts was partially successful using a SpyBite basket.

## Abstract

Biliary cast syndrome (BCS) is a rare complication following orthotopic liver transplantation (OLT), characterized by the formation of casts within the biliary system. We present the case of a 48-year-old woman who developed BCS nine weeks post-transplant. The patient experienced multiple complications, including biloma formation, recurrent anemia, and septic shock. Endoscopic retrograde cholangiopancreatography (ERCP) revealed extensive biliary casts, which were partially removed using a SpyBite basket (Boston Scientific, Marlborough, MA, USA). This case highlights a rare but serious complication of liver transplantation. Early recognition and aggressive treatment are crucial for improving outcomes in liver transplant recipients with BCS.

## Full-text entities

- **Diseases:** BCS (MESH:D013478), septic shock (MESH:D012772), anemia (MESH:D000740)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12255848/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12255848/full.md

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Source: https://tomesphere.com/paper/PMC12255848