# Epstein-Barr Virus-Induced Minimal Change Disease: A Cause of Nephrotic Syndrome in Infectious Mononucleosis

## TL;DR

This paper reports a rare case of kidney disease caused by the Epstein-Barr virus in a young woman with infectious mononucleosis.

## Contribution

The paper highlights EBV as a potential cause of minimal change disease and nephrotic syndrome.

## Key findings

- An 18-year-old woman with EBV-induced IM developed nephrotic syndrome due to minimal change disease.
- The patient showed a rapid response to steroid therapy.
- EBV should be considered in the differential diagnosis of minimal change nephropathy.

## Abstract

Infectious mononucleosis (IM), caused by the Epstein-Barr virus (EBV), typically presents as a self-limiting illness characterized by fever, pharyngitis, and lymphadenopathy. While subclinical renal involvement is not uncommon, acute kidney injury (AKI) and nephrotic syndrome due to EBV are rare. We present the case of an 18-year-old woman with EBV-induced IM complicated by minimal change disease (MCD), resulting in nephrotic syndrome. The patient responded promptly to steroid therapy, highlighting the importance of considering EBV in the differential diagnosis of minimal change nephropathy.