# Late Complications and Adverse Events in Adult Deformity Surgery: A Narrative Review of Event Types, Prevalence, and Information Gaps

**Authors:** Sigurd H. Berven, Justin S. Smith, John T. Street, Eric Klineberg, Yong Qiu, Aboubacar Wague, Stephen J. Lewis

PMC · DOI: 10.1177/21925682251342556 · Global Spine Journal · 2025-07-09

## TL;DR

This review discusses late complications in adult spinal deformity surgery, such as infection and pseudarthrosis, and highlights gaps in current knowledge and management.

## Contribution

The paper provides a narrative review identifying knowledge gaps and areas for improvement in managing late complications of adult spinal deformity surgery.

## Key findings

- Late complications like infection and pseudarthrosis are common in adult spinal deformity surgery.
- Current management has limitations, and there are significant knowledge gaps in defining normal and pathological parameters.
- Future research is needed to improve outcomes and reduce complications in deformity surgery.

## Abstract

Literature review.

The purpose of this paper is to provide a narrative review of late complications in adult deformity surgery, including infection, pseudarthrosis and junctional pathology after deformity correction. This review aims to highlight limitations of current management and identify potential areas of improvement and further study.

We identified common challenges of late complications in adult spinal deformity surgery and performed a directed literature review to summarize the current management and issues encountered in these adverse events. Through consensus, we highlighted the knowledge gaps in the current literature and suggested areas of interest for further study to improve understanding and management of these conditions.

A summary is provided with detailed review of late complications that include infection, pseudarthrosis, junctional pathology, and late decompensation after deformity correction. Important consideration to choosing the appropriate upper and lower instrumented levels, obtaining desired coronal and sagittal alignment, preserving the adjacent ligamentous and muscular structures, obtaining solid arthrodesis, recognizing and optimizing patients for surgery, appropriate pre and post-operative protocols, and appropriately defining normal and pathological parameters.

Recognizing appropriate predictor and outcome variables are important for identifying factors, modifiable and fixed, that may be important to make a clinically important difference in outcomes in the surgical treatment of adult spinal deformity. Future studies to reduce late complications are important to improve value and outcome in adult spinal deformity surgery.

## Full-text entities

- **Diseases:** spinal deformity (MESH:D013122), pseudarthrosis (MESH:D011542), infection (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12254621/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12254621/full.md

## References

111 references — full list in the complete paper: https://tomesphere.com/paper/PMC12254621/full.md

---
Source: https://tomesphere.com/paper/PMC12254621