# Erectile Dysfunction and Peyronie's Disease Following a Severe Case of COVID-19: A Case Report

**Authors:** Eric Qualkenbush, Evan Gibbs, Bryce Baird, Gregory Broderick

PMC · DOI: 10.1155/criu/4329786 · Case Reports in Urology · 2025-07-04

## TL;DR

A man who had severe COVID-19 developed erectile dysfunction and Peyronie's disease after recovery, possibly due to inflammation and treatment positioning.

## Contribution

Highlights a rare urologic complication of severe COVID-19 and its potential iatrogenic causes.

## Key findings

- Severe COVID-19 may lead to erectile dysfunction due to atherosclerosis from systemic inflammation.
- Proned positioning during treatment might cause Peyronie's disease.
- Urologic complications should be considered in post-COVID-19 care.

## Abstract

The COVID-19 pandemic affected millions worldwide. While mainly regarded as a respiratory process, there may be both direct and indirect urologic consequences that are sparsely discussed. This case report describes a patient with a severe COVID-19 infection resulting in a kidney and liver transplant. After recovery, the patient was found to have de novo erectile dysfunction and Peyronie's disease. We suspect the systemic inflammation and vasculopathy leading to liver and renal failure also caused severe atherosclerotic erectile dysfunction. Furthermore, the prone positioning likely represents an iatrogenic etiology of Peyronie's disease. This unique case demonstrates some important considerations from a men's health perspective when caring for patients following a severe COVID-19 infection.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096), Erectile Dysfunction (MONDO:0005362), Peyronie's Disease (MONDO:0008231), liver failure (MONDO:0100192), renal failure (MONDO:0001106)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), Erectile Dysfunction (MESH:D007172), Peyronie's Disease (MESH:D010411), liver and renal failure (MESH:D051437), vasculopathy (MESH:D000090122), inflammation (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12253984/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12253984/full.md

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Source: https://tomesphere.com/paper/PMC12253984