# Three-Dimensional Manufacturing of Mandibular Total Edentulous Simulation Model for In Vitro Studies—Concept and Validation

**Authors:** Joana Mendes, Maria Cristina Manzanares-Céspedes, José L. Esteves, João Fonseca, Lara Coelho, José Manuel Mendes

PMC · DOI: 10.3390/polym17131820 · Polymers · 2025-06-30

## TL;DR

This study creates a 3D model of a mandibular edentulous patient for in vitro research using stereolithography and validates its accuracy.

## Contribution

A novel in vitro 3D simulation model of edentulous mucosa with a reduced alveolar ridge was developed and validated using stereolithography.

## Key findings

- The 3D model achieved a maximal mean displacement of 0.015 mm and minimal mean displacement of 0.004 mm.
- The oral mucosa displacement was approximately 1.6 mm, simulating realistic patient conditions.

## Abstract

Background: Stereolithography is a rapid prototyping and 3D printing technique that creates solid three-dimensional models. An accurate and functional 3D model using stereolithography is invaluable in scientific research, particularly in studies involving edentulous patients. Additive manufacture and CAD systems help achieve accurate measurements and procedures and be easily replicated by lowering human error mistakes. The main objective of this study was to develop an in vitro simulation model with a reduced alveolar ridge with the same characteristics as mandibular edentulous patients using stereolithography. Methods: A mandibular model with a resorbed mandibular crest was scanned, and the STL model was aligned to the XYZ reference system. A reduction in the alveolar ridge corresponding to the mandibular mucosa of an edentulous patient was achieved. A negative model also derived from the original model was made to ensure the space for oral simulation material. A dimensional stability test was performed to validate the model. Results: The maximal mean displacement of the model was 0.015 mm, and the minimal mean displacement was 0.004 mm. The oral mucosa had a displacement of approximately 1.6 mm. Conclusions: An in vitro 3D simulation model of a complete edentulous patient mucosa was achieved.

## Full-text entities

- **Diseases:** Mandibular (MESH:D008338)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12251627/full.md

## References

54 references — full list in the complete paper: https://tomesphere.com/paper/PMC12251627/full.md

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Source: https://tomesphere.com/paper/PMC12251627