Star Polymers as a Reducing Agent of Silver Salt and a Carrier for Silver Nanoparticles
Katarzyna Szcześniak, Grzegorz Przesławski, Jakub Kotecki, Weronika Andrzejewska, Katarzyna Fiedorowicz, Marta Woźniak-Budych, Maciej Jarzębski, Piotr Gajewski, Agnieszka Marcinkowska
TL;DR
Star polymers can create silver nanoparticles that are used in bone cement to prevent infections without harming mechanical strength.
Contribution
A new method for synthesizing star polymers that reduce silver salt and carry nanoparticles for biomedical use.
Findings
Star polymers successfully reduced silver nitrate to form spherical silver nanoparticles.
Hybrid nanomaterials incorporated into bone cement showed antibacterial effects against E. coli.
The modified bone cement maintained acceptable compressive strength and biocompatibility.
Abstract
Star polymers—macromolecules featuring multiple arms radiating from a central core—offer unique potential for biomedical applications due to their tunable architecture, multifunctionality and ability to incorporate stimuli-responsive and biocompatible components. In this study, functional star polymers with oligo (ethylene glycol) methyl ether methacrylate (OEOMA) arms and 2-(dimethylamino)ethyl methacrylate (DMAEMA) core units were synthesized via atom transfer radical polymerization (ATRP) using the “arm-first” strategy. The star polymers were used as nanoreactors for the in situ reduction of silver nitrate to form silver nanoparticles (AgNPs) without additional reducing agents. UV–Vis spectroscopy confirmed the formation of spherical AgNPs with absorption maxima around 430 nm, and transmission electron microscopy revealed uniform particle morphology. These hybrid nanomaterials…
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Taxonomy
TopicsAdvanced Polymer Synthesis and Characterization · Polymer Surface Interaction Studies · Antimicrobial agents and applications