# Bilateral Sylvian fissure lipomas with angiomatous component: A case report

**Authors:** Mireille M. de Vries, Nadine Oosterhof, Carine Martins Jarnalo, Marjolein Dremmen, Janet de Beukelaar, Nienke Katier

PMC · DOI: 10.1016/j.radcr.2025.05.110 · 2025-06-26

## TL;DR

This paper reports a rare case of bilateral lipomas in the Sylvian fissure of a 28-year-old woman, discovered during a routine MRI for headache.

## Contribution

The novelty lies in the first reported case of bilateral Sylvian fissure lipomas with an angiomatous component.

## Key findings

- MRI revealed bilateral extra-axial perisylvian lesions consistent with lipomas.
- The case highlights the importance of recognizing this rare condition for accurate diagnosis and management.

## Abstract

Sylvian fissure lipomas are rare congenital malformations, with few cases reported in the literature. We present the case of a 28-year-old woman who consulted a neurologist for headache during pregnancy. Brain magnetic resonance imaging (MRI) showed bilateral extra-axial perisylvian lesions as an incidental finding. The MRI characteristics led to the diagnosis of bilateral Sylvian fissure lipomas with angiomatous component. To our knowledge, no previous cases of bilateral Sylvian fissure lipomas have been reported. This article provides an overview of the literature on Sylvian fissure lipomas, including their prevalence, pathophysiology, differential diagnosis, and management, to aid in their timely recognition and appropriate evaluation.

## Full-text entities

- **Diseases:** congenital malformations (OMIM:163000), headache (MESH:D006261), Sylvian fissure lipomas (MESH:D019305)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12250946/full.md

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Source: https://tomesphere.com/paper/PMC12250946