# Reconstructive Arthrodesis for Advanced Ankle and Subtalar Joint Destruction in Neuropathic and Infected Feet

**Authors:** Martin Korbel, Jaromír Šrot, Pavel Šponer

PMC · DOI: 10.3390/jcm14134516 · Journal of Clinical Medicine · 2025-06-25

## TL;DR

This study examines the outcomes of reconstructive surgery for severe ankle and foot damage, finding it can be a viable alternative to amputation in some high-risk patients.

## Contribution

The study provides real-world evidence on the effectiveness of limb-preserving surgery for advanced ankle and subtalar joint destruction.

## Key findings

- Successful arthrodesis was achieved in 74% of cases.
- Tibiotalocalcaneal arthrodesis with external fixation had the lowest union rate at 17%.
- 42% of patients experienced surgical site infections or abscesses.

## Abstract

Background/Objectives: Advanced destruction of the ankle and subtalar joints due to neuropathy, chronic infection, or inflammatory conditions presents a major surgical challenge, often resulting in limb amputation. This descriptive retrospective study aims to evaluate outcomes of reconstructive surgery in patients, in whom limb preservation was prioritized over amputation despite significant soft tissue and osseous involvement. Methods: Between January 2013 and December 2022, 31 reconstructive procedures were performed on 29 patients (16 women and 13 men) with severe hindfoot deformities. Etiologies included Charcot arthropathy (55%), osteomyelitis (25%), combined pathology (10%), and rheumatoid deformity with skin defect (10%). Surgical procedures included tibiotalocalcaneal arthrodesis (39%), astragalectomy with tibiocalcaneal arthrodesis (32%), tibiotalar arthrodesis (23%), and multistage procedures (6%). Fixation methods varied based on the extent of deformity and infection. The union was assessed via radiographs and CT imaging, and outcomes were statistically analyzed using Fisher’s exact test. Results: Successful arthrodesis was achieved in 74% of cases (23/31). The union rate was significantly influenced by the type and level of fixation (p = 0.0199), with the lowest rate observed in tibiotalocalcaneal arthrodesis using external fixation (17%). Complications included surgical site infection or abscess in 42% of cases, requiring reoperation in 35%. Limb amputation was ultimately necessary in five patients (16%). Conclusions: Despite high complication rates, limb-preserving reconstructive surgery remains a viable alternative to amputation in selected high-risk patients with severe hindfoot pathology. Appropriate preoperative planning, tailored surgical strategy, and patient compliance are essential to achieving functional limb salvage and restoring weight-bearing capacity.

## Linked entities

- **Diseases:** osteomyelitis (MONDO:0005246)

## Full-text entities

- **Diseases:** Charcot arthropathy (MESH:D007592), rheumatoid deformity (MESH:D011695), Ankle (MESH:D016512), neuropathy (MESH:D009422), abscess (MESH:D000038), infection (MESH:D007239), skin defect (MESH:D012868), inflammatory (MESH:D007249), osteomyelitis (MESH:D010019), deformity (MESH:D009140), Destruction (MESH:D008105)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12250316/full.md

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Source: https://tomesphere.com/paper/PMC12250316