# Characterizing Spinal Decompression for Foot Drop Caused by Lumbar Degenerative Disease: A Systematic Review and Meta-Analysis of Cohorts

**Authors:** Christian A. Than, May Y. Hajeir, Lamees M. Al Darwashi, Kelly Silnes, Aslam Mohamed Haroon, Angelique K. Valiotis, Diana Shibib, Yasmine J. Khair, Hugh Milchem, Persidiu Iancu, Zaher Dannawi

PMC · DOI: 10.3390/jcm14134470 · Journal of Clinical Medicine · 2025-06-24

## TL;DR

This study reviews and analyzes the effectiveness of spinal surgery for foot drop caused by lower back issues, showing that most patients improve but some do not.

## Contribution

The study provides a comprehensive meta-analysis of muscle strength recovery after lumbar decompression for foot drop due to lumbar degenerative disease.

## Key findings

- 60% of patients achieved significant muscle strength recovery after surgery.
- 82% of patients showed at least one grade improvement in muscle strength.
- 18% of patients experienced no improvement in muscle strength post-surgery.

## Abstract

Background/Objectives: There exists a need to capture the current landscape of the literature for lumbar decompression on muscle strength, as measured by manual muscle testing (MMT), in cohorts with foot drop secondary to lumbar degenerative disease (LDD). Methods: A literature search of PubMed, EMBASE, CINAHL, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Scopus, and Web of Science was conducted from each database’s inception to 21 March 2025. Eligible studies reported patients with LDD-related foot drop treated surgically. This review was registered in PROSPERO (ID: CRD42024550980). Results: A total of 20 studies comprising 918 patients met the eligibility criteria, with most cases attributable to lumbar disc herniation (79% of patients, 95% CI: 0.72–0.85, I2 = 96%) or spinal stenosis (22% of patients, 95% CI: 0.15–0.30, I2 = 96%). Following surgery, 60% of patients (95% CI: 0.44–0.75, I2 = 97%) achieved an MMT score of 4–5, indicating recovery, while 82% (95% CI: 0.76–0.88, I2 = 89%) demonstrated an improvement of at least one MMT grade. No improvement was seen in 18% of patients (95% CI: 0.12–0.24, I2 = 89%). For pain, the preoperative VAS mean was 5.91 (95% CI: 4.21–7.60, I2 = 99%), while the postoperative mean was 1.00 (95% CI: −0.05–2.06, I2 = 99%). Overall complications were reported at 1% (95% CI: −0.00–0.02, I2 = 0%). Conclusions: Lumbar decompression achieves clinically meaningful recovery of LDD-induced foot drop. However, this meta-analysis highlights the overlooked portion of patients who will not respond, providing a sequential approach for future investigation of these cohorts through foundational evidence of the present literature base.

## Full-text entities

- **Diseases:** LDD (MESH:D019636), spinal stenosis (MESH:D013130), lumbar disc herniation (MESH:C535531), pain (MESH:D010146), Foot Drop (MESH:D020427)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

45 references — full list in the complete paper: https://tomesphere.com/paper/PMC12249779/full.md

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Source: https://tomesphere.com/paper/PMC12249779