# A Discrete Choice Experiment to Assess Cat Owners’ Preferences for Topical Antiparasitics and the Comparative Ease of Use of a Combined Selamectin and Sarolaner Formulation: An International Survey

**Authors:** Constantina N. Tsokana, George Valiakos, Kennedy Mwacalimba, Danielle Riley, Ashley Enstone, Robin Wyn, Tom Metcalf, Emily Melchior, Eleni Pavlidou, Andrea Wright

PMC · DOI: 10.3390/ani15131985 · Animals : an Open Access Journal from MDPI · 2025-07-06

## TL;DR

This study explores what cat owners prefer in antiparasitic treatments, finding that ease of use and safety are key factors in their choices.

## Contribution

The study introduces a combined selamectin and sarolaner formulation and identifies its usability advantages through a discrete choice experiment.

## Key findings

- The selamectin–sarolaner formulation was characterized by minimal smell, less stickiness, and quick drying.
- Cat owners preferred the selamectin–sarolaner product profile due to ease of application and safety features.
- Demographic factors like age, gender, and insurance influenced cat owners’ treatment preferences.

## Abstract

Cat owners are involved in their cats’ healthcare, including the prevention of parasitic diseases. However, we do not fully understand the factors that influence their preferences when choosing antiparasitic treatments. This study, comprising three phases, aimed to fill that gap. In Phase 1, several features and usability aspects of seven topical antiparasitics were assessed. In Phase 2, cat owners evaluated their application experience with blinded products representing three topical antiparasitics. Phase 3 included interviews with pet owners and veterinary experts to identify and validate the product attributes most valued by pet owners when choosing topical antiparasitics. These product attributes were then used in an international survey involving 1040 cat owners from different countries (Australia/New Zealand, Canada, Greece/Spain, and the UK) to understand their preferences among product profiles mirroring four topical antiparasitics. Phase 1 showed that the selamectin–sarolaner formulation had minimal smell, was not sticky, and dried quickly. In Phase 2, participants characterized the blinded product representing the selamectin–sarolaner formulation as having a seamless application, rapid dispensing, and a sense of control during application. In Phase 3, a global sample of cat owners showed preference for the product profile mirroring the selamectin–sarolaner treatment. Factors like age, gender, and insurance influenced their choices. The ability to confirm successful administration, age restrictions, ease of application, and the time before the cat could sit on furniture following application significantly influenced cat owners’ preference for the product profile mirroring the selamectin–sarolaner formulation over at least one comparator treatment. These findings indicate that cat owners prioritize ease of use and safety, which can help veterinarians make better recommendations for pet treatments, leading to healthier cats.

Cat owners are involved in their cats’ healthcare, including the prevention of parasitic diseases. However, a comprehensive understanding of their preferences for feline antiparasitics is lacking. This study addresses this gap through a multifaceted methodology comprising three phases. In Phase 1, the physical properties and usability aspects of seven topical antiparasitic formulations were assessed. Within Phase 2, an ease-of-use study was conducted to evaluate the cat owners’ application experience with deidentified products representing three topical antiparasitics. Phase 3 included the identification and validation of product attributes most valued by pet owners through interviews with cat owners and veterinary experts. The product attributes identified informed the subsequent quantitative discrete choice experiment (DCE), which involved 1040 cat owners from different countries (Australia/New Zealand, Canada, Greece/Spain, and the UK) and aimed to analyze their preferences based on choices among product profiles mirroring four topical antiparasitics: selamectin–sarolaner, moxidectin–fluralaner, moxidectin–imidacloprid, and eprinomectin–esafoxolaner–praziquantel. Phase 1 showed that the selamectin–sarolaner formulation exhibits minimal odor, less stickiness, and less drying time. The ease-of-use study (Phase 2) showed that the blinded product representing the selamectin–sarolaner formulation was characterized by seamless application, rapid dispensing, and a sense of control during application. The quantitative DCE study (Phase 3) indicated a preference for the product profile mirroring the selamectin–sarolaner formulation among a global sample of cat owners. Demographic characteristics such as gender, age, and insurance status influenced their preferences. Key predictors for preferring the selamectin–sarolaner formulation over at least one comparator treatment included the ability to confirm successful administration, age restrictions, ease of application, and the time before the cat could sit on furniture following administration. These findings suggest that cat owners prioritize ease of use, safety, and overall user experience, providing valuable guidance for veterinary practitioners to make informed treatment recommendations.

## Linked entities

- **Chemicals:** selamectin (PubChem CID 9578507), sarolaner (PubChem CID 73169092), moxidectin (PubChem CID 9832912), fluralaner (PubChem CID 25144319), imidacloprid (PubChem CID 86287518), eprinomectin (PubChem CID 6450531), esafoxolaner (PubChem CID 76961292), praziquantel (PubChem CID 4891)

## Full-text entities

- **Diseases:** parasitic diseases (MESH:D010272)
- **Chemicals:** praziquantel (MESH:D011223), fluralaner (MESH:C000591860), Sarolaner (MESH:C000623191), esafoxolaner (-), imidacloprid (MESH:C082359), eprinomectin (MESH:C101434), moxidectin (MESH:C027837), Selamectin (MESH:C414354)
- **Species:** Felis catus (cat, species) [taxon 9685]

## Full text

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC12248694/full.md

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Source: https://tomesphere.com/paper/PMC12248694