# Endophthalmitis caused by Abiotrophia defectiva with initial presentation as retinal vasculitis: a case report

**Authors:** Xiaojie Lu, Bei Liu, Tiemei Yie, Weiwei Wang

PMC · DOI: 10.1186/s13256-025-05358-0 · Journal of Medical Case Reports · 2025-07-11

## TL;DR

A rare case of eye infection caused by Abiotrophia defectiva, initially mistaken for retinal vasculitis, highlights the importance of quick diagnosis for better vision outcomes.

## Contribution

This case report documents a rare presentation of Abiotrophia defectiva-induced endophthalmitis mimicking retinal vasculitis.

## Key findings

- Abiotrophia defectiva was identified as the causative agent of endophthalmitis in a patient initially diagnosed with retinal vasculitis.
- Prompt treatment improved the patient's visual acuity after initial symptoms worsened rapidly.
- The case underscores the need for considering atypical pathogens in postoperative ocular infections.

## Abstract

Abiotrophia defectiva is primarily known for its association with endocarditis rather than intraocular infections. We reported a case of endophthalmitis caused by Abiotrophia defectiva, presenting as retinal vasculitis in its early stages, a phenomenon rarely documented in literature.

A 50-year-old Han Chinese man presented to the hospital with decreased vision in his left eye. Examination revealed mild vitritis, papilledema, retinal hemorrhages, and peripheral vascular sheathing in the left eye, raising suspicion of retinal vasculitis. In the following hours, his condition worsened dramatically, with the development of hypopyon and severe vitritis obscuring the visualization of the fundus, suggesting endophthalmitis. He subsequently underwent urgent anterior chamber irrigation, vitreous tap, and intravitreal injection. As the symptoms did not improve, a vitrectomy was performed. The culture results identified the presence of Abiotrophia defectiva. Following prompt and effective treatment, the patient’s visual acuity showed improvement.

This report delineates a rare case of endophthalmitis caused by Abiotrophia defectiva initially presenting as retinal vasculitis. It emphasizes the need for prompt recognition and treatment of atypical pathogens in postoperative ocular infections to enhance visual outcomes.

## Linked entities

- **Diseases:** endophthalmitis (MONDO:0016047), retinal vasculitis (MONDO:0006950)

## Full-text entities

- **Diseases:** decreased vision (MESH:D014786), retinal hemorrhages (MESH:D012166), papilledema (MESH:D010211), Endophthalmitis (MESH:D009877), retinal vasculitis (MESH:D031300), endocarditis (MESH:D004696), intraocular infections (MESH:D064090), ocular infections (MESH:D015817)
- **Species:** Homo sapiens (human, species) [taxon 9606], Abiotrophia defectiva (species) [taxon 46125]

## Full text

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## Figures

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Source: https://tomesphere.com/paper/PMC12247376