# Extensive Cerebral Venous Sinus Thrombosis at High Altitude

**Authors:** Jamal Ouachaou, Driouich Aicha, Mohammed Sidayne, Fatimazahrae El Khettab, Youssef Zarrouki

PMC · DOI: 10.7759/cureus.85742 · Cureus · 2025-06-10

## TL;DR

A 27-year-old woman developed a rare and severe brain condition after climbing to high altitude in the Atlas Mountains.

## Contribution

This paper presents a rare case linking high-altitude exposure to cerebral venous sinus thrombosis.

## Key findings

- A 27-year-old woman developed extensive cerebral venous sinus thrombosis during a high-altitude expedition.
- The case highlights the potential for high altitude to contribute to rare cerebrovascular events.
- The paper discusses possible mechanisms behind this unusual clinical observation.

## Abstract

Rapid ascent to altitudes above 8,000 feet (2,500 meters) is known to be associated with acute mountain sickness (AMS), but its role as a cause of cerebrovascular disorders is rarely described. Cerebral venous sinus thrombosis is a rare and potentially fatal condition that can frequently be misdiagnosed.

In this article, we report an unusual case of a 27-year-old woman who developed an extensive cerebral venous sinus thrombosis (CVST) during an expedition in the Atlas Mountains. The underlying mechanisms explaining this event will be discussed in light of this clinical observation.

## Linked entities

- **Diseases:** acute mountain sickness (MONDO:0021811)

## Full-text entities

- **Diseases:** CVST (MESH:D012851), AMS (MESH:D000532), cerebrovascular disorders (MESH:D002561)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12246765/full.md

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Source: https://tomesphere.com/paper/PMC12246765