# Effects of meteorological factors on outpatient visits for chronic rhinosinusitis in Wuhan, China (2018–2019): a time-series analysis

## TL;DR

This study found that low temperatures are linked to increased outpatient visits for chronic rhinosinusitis in Wuhan, China, with effects varying by age group.

## Contribution

The study introduces a detailed time-series analysis of meteorological effects on chronic rhinosinusitis outpatient visits in a specific geographic region.

## Key findings

- Low temperatures significantly increased outpatient visits for chronic rhinosinusitis.
- Childhood and younger individuals showed a negative correlation between temperature and outpatient visits.
- Relative humidity and precipitation had no significant association with outpatient visits.

## Abstract

Studies examining associations between meteorological factors and outpatient visits for chronic rhinosinusitis (CRS) are limited. This study aimed to investigate the effects of daily mean temperature, relative humidity (RH) and precipitation on outpatient visits for CRS.

Electronic records of CRS outpatient visits were collected from Tongji hospital in Wuhan, China from January 1, 2018 to December 31, 2019. Daily meteorological data were obtained from the Wuhan Meteorological Bureau during the same period. A generalized additive negative binomial regression model combined with a distributed lag non-linear model (DLNM) was employed to analyze the lag-exposure-response relationship between meteorological factors and the number of CRS outpatient visits. Stratified analyses were conducted to identify potential effect modifications by age and season.

A total of 14,259 CRS outpatient visits were recorded. Relative humidity and precipitation showed no significant association with daily CRS visits, whereas low temperatures significantly elevated CRS outpatient visits. Specifically, extreme temperature (−1.8°C, 1st percentile) was found to be associated with 1.946 (95% CI 1.273–2.973) times the risk of outpatient visits due to CRS, compared to the reference value of 32.9°C. Furthermore, the number of outpatient visits for childhood and younger individuals with CRS showed a negative correlation with temperatures, whereas middle-aged individuals and older adult individuals showed no such correlation.

This study suggests that meteorological phenomena may have detrimental effects on health, thereby contributing to a better understanding of the environmental risk factors associated with this disease.