# Utilizing SS-OCT and 3D parametric modeling to enhance IOL position prediction in cataract patients with long axial length

**Authors:** Chuang Li, Bin Luo, Xiaoling Luo, Liying Zhang, Qiang Li, Wei Peng

PMC · DOI: 10.3389/fmed.2025.1604224 · Frontiers in Medicine · 2025-06-27

## TL;DR

This study shows that using SS-OCT and 3D modeling improves the prediction of intraocular lens position in cataract patients with long eye lengths.

## Contribution

The study introduces SS-OCT and 3D parametric modeling as a better method for predicting IOL position in long axial length eyes.

## Key findings

- LEP is a better predictor of postoperative IOL position than preoperative ACD in long axial length eyes.
- LEP showed the highest correlation with IOL position in ultra-long eyes (AL ≥ 28.0 mm).
- 3D parametric modeling enhances the accuracy of IOL position prediction in cataract surgery.

## Abstract

This study aimed to investigate the biological characteristics of the lens and explore the factors influencing the postoperative position of intraocular lens (IOL) using swept-source optical coherence tomography (SS-OCT) in cataract patients with long axial length (AL).

This retrospective study enrolled 110 cataract patients who underwent uneventful cataract surgeries. The preoperative and postoperative biometric parameters were obtained using IOLMaster 700. The average lens density (ALD) was analyzed using Fiji ImageJ. The biological characteristics of cataracts were analyzed using three-dimension (3D) parametric modeling software, Pro/Engineer Wildfire 5.0.

The lens equator position (LEP) showed positive correlation with the preoperative anterior chamber depth (ACD), lens equatorial diameter (LED), and lens vaulting (LV). The postoperative position of the IOL showed positive correlation with the preoperative ACD and LEP (r = 0.432, p < 0.05; r = 0.657, p < 0.05). The LEP demonstrated a higher correlation with the postoperative position of the IOL than with the preoperative ACD (p < 0.05). The LEP displayed the highest correlation with the postoperative position of the IOL (r = 0.686, p < 0.05) in the subgroup of ultra-long eyes (AL ≥ 28.0 mm).

The LEP, derived from the SS-OCT and 3D parametric modeling, was a better predictor of postoperative IOL position than the preoperative ACD. This methodology provides a robust basis for accurately predicting the effective lens position in cataract patients with long AL.

## Linked entities

- **Diseases:** cataract (MONDO:0005129)

## Full-text entities

- **Diseases:** cataract (MESH:D002386)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC12245857/full.md

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Source: https://tomesphere.com/paper/PMC12245857