# Fetal mortality before and during the COVID-19 pandemic: a single-center cohort study in Rio de Janeiro, Brazil

**Authors:** Gustavo Yano Callado, Edward Araujo, Carolina Aquino Guedes Ramos, José Maria Andrade Lopes, Danielle Negri, Maria Elizabeth Lopes Moreira, Renato Augusto Moreira de Sá

PMC · DOI: 10.1590/1806-9282.20250382 · Revista da Associação Médica Brasileira · 2025-07-07

## TL;DR

This study compares fetal deaths before and during the COVID-19 pandemic in a private hospital in Rio de Janeiro, finding no significant differences in outcomes.

## Contribution

The study provides insights into fetal mortality during the pandemic in a private healthcare setting in Brazil.

## Key findings

- Fetal mortality rates were similar before and during the pandemic.
- No significant differences were found in maternal or fetal characteristics between the two periods.
- Despite the presence of COVID-19 in some pregnancies, no disparities in fetal death causes were observed.

## Abstract

The aim of this study was to compare the characteristics of pregnancies that resulted in fetal death before and during the COVID-19 pandemic in a private maternity hospital in Rio de Janeiro, Brazil.

This retrospective cohort study considered all pregnancies that ended in fetal death in a private maternity hospital in Rio de Janeiro, Brazil, from January 2018 to December 2021. Maternal and fetal characteristics were compared between the periods before the pandemic and during the pandemic. Data were extracted from electronic medical records, and statistical analyses included Student's t-test, chi-square test, and Fisher's exact test where applicable.

Among 41,162 deliveries at Casa de Saúde Perinatal, 88 (0.21%) resulted in fetal death, with 38 (43.2%) occurring pre-pandemic (2018–March 2020) and 50 (56.8%) during the pandemic (March 2020–2021). Maternal demographics, comorbidities, and prepartum complications showed no statistically significant differences between groups. COVID-19 infection was identified in 12% of the pandemic-group pregnancies, but no significant disparities in fetal death causes or abnormalities were found.

No significant differences were observed in maternal or fetal characteristics, prepartum complications, or fetal mortality rates between the pre-pandemic and pandemic periods in this private hospital setting. However, this does not reflect the broader Brazilian healthcare reality, where disparities in access and resources may have influenced outcomes differently.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), fetal death (MESH:D005313)

## Full text

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12245052/full.md

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Source: https://tomesphere.com/paper/PMC12245052