# Computed tomography versus sleep endoscopy (DISE) to predict the effectiveness of mandibular advancement device in adult patients with obstructive sleep apnea: A systematic review

## TL;DR

This study compares CT scans and sleep endoscopy to predict the success of a device used to treat sleep apnea in adults.

## Contribution

The paper systematically reviews the effectiveness of CT versus DISE in predicting mandibular advancement device success for OSA.

## Key findings

- CT provides detailed anatomical airway data but lacks dynamic simulation of sleep conditions.
- DISE offers real-time visualization of airway collapse during sleep, potentially improving prediction accuracy.
- Conflicting study results highlight the complexity of predicting treatment outcomes for OSA.

## Abstract

Obstructive sleep apnea (OSA) has a high prevalence in the global population and is a significant sleep disorder. One of the non-invasive options to treat obstructive sleep apnea is the mandibular advancement device. 2 methods can help predict the success of mandibular advancement devices, and they are Neck computed tomography (CT) and Drug-induced Sleep endoscopy (DISE). The objective of this study was to determine which method is better at predicting the success of a mandibular advancement device in the treatment of obstructive sleep apnea.

PubMed, Embase and Web of Science Core Collection databases were comprehensively searched. A total of 1809 was obtained through the extensive search of the three databases mentioned above (Embase = 952; PubMed = 508; Web of Science = 349). The exclusion criteria were studies lacking clear and replicable methodologies; research involving pediatric and adolescent participants, as well as individuals with craniofacial malformations; and Animal studies, conference abstracts, editorials, case reports, book chapters, and review articles.

Based on the inclusion criteria, mainly because of the lack of direct comparison between CT and DISE for the prediction of MAD success, two articles were selected for this systematic review. The conflicting findings between the two studies underscore the complexity of OSA management and challenges associated with predicting treatment outcomes using different diagnostic modalities.

Although CT offers detailed anatomical information regarding airway morphology, DISE provides dynamic visualization of upper airway collapse during sleep, which may better simulate real-life conditions and MAD responses.