# Infectious Scleritis Masquerading as Isolated Orbital Cellulitis: A Case Report

**Authors:** Yazeed J AlHaqbani, Almoayad M Makrami, Fatimah N Alzaher, Majed F Alsubaie, Abdulaziz S Khoshaim

PMC · DOI: 10.7759/cureus.85714 · Cureus · 2025-06-10

## TL;DR

A woman with eye symptoms initially diagnosed with orbital cellulitis was later found to have infectious scleritis caused by Pseudomonas aeruginosa.

## Contribution

This case report highlights the rare presentation of infectious scleritis masquerading as orbital cellulitis and emphasizes the need for combined medical and surgical treatment.

## Key findings

- Initial diagnosis of orbital cellulitis was incorrect; the patient was later found to have infectious scleritis.
- Pseudomonas aeruginosa was identified as the causative agent through culture after surgical intervention.
- Effective management of infectious scleritis requires a combined medical and surgical approach.

## Abstract

A woman in her fifties was presented to the emergency room with eye pain, swelling, redness, and reduced vision. The examination revealed periorbital swelling, limited extraocular motility, tenderness, and conjunctival chemosis, with thinning observed nasally at the site of prior pterygium repair. The anterior chamber was quiet, and B-scan (ultrasonography) revealed retino-choroidal thickening. Computed tomography (CT) scan results indicated septal cellulitis with clear sinuses. Laboratory workups were negative. The patient was diagnosed with orbital cellulitis and was admitted and treated accordingly. However, the patient developed recurrent attacks with hypopyon, which prompted another course of management. The patient was presented again, displaying an aggressive clinical picture, and there was a focal calcified plaque over the nasal area, suggesting necrotizing scleritis. B-scan shows T-sign and conjunctival recession, scleral scraping, debridement, and subconjunctival antibiotic injection were performed. A positive culture for Pseudomonas aeruginosa was identified. An agreement on the management of this ocular condition lacks a clear guideline. However, most infectious scleritis cases mandate a combined approach involving medical treatment and surgical debridement.

## Linked entities

- **Diseases:** orbital cellulitis (MONDO:0006881), scleritis (MONDO:0001718), infectious scleritis (MONDO:0958264)

## Full-text entities

- **Diseases:** eye pain (MESH:D058447), tenderness (MESH:D063806), swelling (MESH:D004487), ocular condition (MESH:D020763), vision (MESH:D014786), Orbital Cellulitis (MESH:D054517), periorbital swelling (MESH:D006261), cellulitis (MESH:D002481), conjunctival recession (MESH:D003229), Infectious Scleritis (MESH:D015423)
- **Species:** Pseudomonas aeruginosa (species) [taxon 287], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12244440/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12244440/full.md

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Source: https://tomesphere.com/paper/PMC12244440